ArticleAnnals of the Royal College of Surgeons of England2008
D-Dimer in the diagnosis of deep vein thrombosis following total hip and knee replacement: a prospective study.
Article in Annals of the Royal College of Surgeons of England, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic value of D-dimer in screening for deep vein thrombosis after total joint arthroplasty: a meta-analysis.Frontiers in surgery · 2026Pooled it
- Apelin-13 as a novel diagnostic laboratory biomarker in thromboembolic disorders: a review of literature with prospective insights.International journal of emergency medicine · 2024Review
- Identifying high-risk groups for deep vein thrombosis after primary total knee arthroplasty using preoperative Caprini scores and D-dimer levels.Journal of orthopaedic surgery and research · 2024Article
- Utility of D-dimer in total joint arthroplasty.World journal of orthopedics · 2023Review
- Venous Thromboembolism Prophylaxis in Elective Spine Surgery.Global spine journal · 2021Article
- D-Dimer Levels Are Not Elevated in SARS-CoV-2 IgG Positive Patients Undergoing Elective Orthopedic Surgery.Journal of clinical medicine · 2021Article
- Serum D-dimer should not be used in the diagnosis of venous thromboembolism within 28 days of total knee replacement surgery.Knee surgery & related research · 2020Article
- Diagnostic value of platelet-derived microparticles in pulmonary thromboembolism: A population-based study.Experimental and therapeutic medicine · 2018Article
- Plasma D-dimer is not useful in the prediction of deep vein thrombosis after total knee arthroplasty in patients using rivaroxaban for thromboprophylaxis.Journal of orthopaedic surgery and research · 2018Article
- Combined Intravenous and Intra-Articular Tranexamic Acid in Simultaneous Bilateral Total Knee Arthroplasty without Tourniquet Use.JB & JS open access · 2017Article
- The great deception: tranexamic acid and extensive pulmonary emboli.BMJ case reports · 2013Article
- Clinical Impact of Coagulation and Fibrinolysis Markers for Predicting Postoperative Venous Thromboembolism in Total Joint Arthroplasty Patients.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
- Time Course of Inflammatory and Procoagulant Markers in the Early Period After Total Hip Replacement.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisObservational
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5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe merit of using D-dimer estimations in patients following total hip and knee replacement has been previously questioned. A survey of radiology protocols in 70 hospitals ascertained that the test continues to be mandatory in 51 prior to formal radiological investigation of suspected deep vein thrombosis (DVT) in this patient population. PATIENTS AND
methodsIn this study, D-dimer levels were measured pre-operatively and during the first 7 days following primary total hip and knee replacement to estimate the range of normal values in these patients.
resultsAll 78 patients were ultrasonographically shown to be clear of DVT. D-Dimer levels were significantly raised in all patients at all measurements during the first week. Levels after total knee replacement were higher than after total hip replacement. Comparison was made with an age-matched group who had a proven DVT. There was no difference in D-dimer levels between patients with or without a DVT.
conclusionsThe use of this test in this patient group is a waste of resource and merely delays appropriate radiological investigation and treatment.
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