ArticleEuropean journal of epidemiology2008
Electrocardiographic criteria of left ventricular hypertrophy in general population.
Article in European journal of epidemiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 58 citations in OpenAlex.
- Combined effects of hypertension and arterial stiffness on target organ damage among community-based screening participants.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Observational
- Performance of Electrocardiographic Criteria for Echocardiographically Diagnosed Left Ventricular Hypertrophy in Chinese Hypertensive Patients.American journal of hypertension · 2020Article
- Subgroup analysis of the influence of body mass index on the association between serum lipids and cognitive function in Chinese population.Lipids in health and disease · 2020Article
- Conventional and new electrocardiographic criteria for hypertension-mediated cardiac organ damage: A narrative review.Journal of clinical hypertension (Greenwich, Conn.) · 2019Review
- Association between electrocardiographic and echocardiographic markers of stage B heart failure and cardiovascular outcome.ESC heart failure · 2017Article
- Population-based values and abnormalities of the electrocardiogram in the general Dutch population: The LifeLines Cohort Study.Clinical cardiology · 2017Observational
- Models for improved diagnosis of left ventricular hypertrophy based on conventional electrocardiographic criteria.BMC cardiovascular disorders · 2017Article
- Validity of electrocardiographic criteria for increased left ventricular mass in young patients in the general population.World journal of cardiology · 2017Article
- The ROVIGO study (risk of vascular complications: impact of genetics in old people): protocol, study design, and preliminary results of the initial survey : cardiovascular epidemiology in the elderly.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2015Article
- Detection of left ventricular hypertrophy by the R-wave voltage in lead aVL: population-based study.Clinical research in cardiology : official journal of the German Cardiac Society · 2013Article
- Relation of central and brachial blood pressure to left ventricular hypertrophy. The Czech Post-MONICA Study.Journal of human hypertension · 2012Article
- Prevalence and determinants of left ventricular hypertrophy in hypertensive patients at a primary care clinic.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2012Article
- Changes in electrocardiographic left ventricular hypertrophy and risk of major cardiovascular events in isolated systolic hypertension: the LIFE study.Journal of human hypertension · 2011Article
- The Shanghai Changfeng Study: a community-based prospective cohort study of chronic diseases among middle-aged and elderly: objectives and design.European journal of epidemiology · 2010Article
- The Generation R Study: design and cohort update 2010.European journal of epidemiology · 2010Article
- Early influences on cardiovascular and renal development.European journal of epidemiology · 2010Review
- [Cardiac sequelae of hypertension].Der Internist · 2009Review
- Left ventricular hypertrophy by Sokolow-Lyon voltage criterion predicts mortality in overweight hypertensive subjects.Journal of human hypertension · 2009Article
- The Rotterdam Study: 2010 objectives and design update.European journal of epidemiology · 2009Article
- Recent trends in cardiovascular epidemiology.European journal of epidemiology · 2009Article
Corrections and comments
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Authors and funding
15 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The question on whether the electrocardiographic criteria are reliable for detection of left ventricular hypertrophy (LVH) and play a role in predicting outcome is open. Answer can only proceed from population-based studies over unselected people followed up for years. In this study, 1,699 subjects from general population underwent echocardiogram and standard electrocardiogram (ECG) codified for LVH with Minnesota code and with other five methods. Other items were also recorded and used as covariables. Left ventricular mass index (LVMI) was 127.6 +/- 44.9 g m(-2) in men and 120.8 +/- 41.2 g m(-2 )in women, and correlated directly with age in both genders. Prevalence of echocardiographic LVH was 36.6% in men and 53.4% in women. LVMI correlated directly with the Sokolow-Lyon score in both genders at any age, with the Romhilt-Estes, Cornell and R(aVL) scores in all subjects but elderly men, and with the Lewis score in men and women aged < or =69 years. Sensitivity and the predictive value of electrocardiographic tests, as well as the prevalence of LVH diagnosed with electrocardiographic criteria, were always low. Specificity was high for all the tests, and in particular for the Cornell index. Only when diagnosed with echocardiogram or with the Sokolow-Lyon criterion, LVH was an independent predictor of mortality. We conclude that electrocardiographic tests cannot be used as a surrogate of echocardiogram in detecting LVH in the general population because their positive predictive value (PPV) is unacceptably low. On the contrary, they could replace echocardiography in the follow up and for prediction of outcome, when LVH has previously been correctly diagnosed with other methods.
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