ArticleJournal of clinical microbiology2008
High-throughput genotyping of Salmonella enterica serovar Typhi allowing geographical assignment of haplotypes and pathotypes within an urban District of Jakarta, Indonesia.
Article in Journal of clinical microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Temporal fluctuation of multidrug resistant salmonella typhi haplotypes in the mekong river delta region of Vietnam.PLoS neglected tropical diseases · 2011Trial
- Determining genotype and antimicrobial resistance of Salmonella Typhi in environmental samples by amplicon sequencing.PLoS neglected tropical diseases · 2025Article
- Genotypic Diversity amongInternational journal of clinical microbiology · 2024Article
- Genomic Investigation ofMicroorganisms · 2023Article
- Validation of the Nelwan Score as a screening tool for the diagnosis of typhoid fever in adults in Indonesia.PloS one · 2023Article
- Hotspots sequences of gyrA, gyrB, parC, and parE genes encoded for fluoroquinolones resistance from local Salmonella Typhi strains in Jakarta.BMC microbiology · 2022Article
- Spatial-temporal and phylogenetic analyses of epidemiologic data to help understand the modes of transmission of endemic typhoid fever in Samoa.PLoS neglected tropical diseases · 2022Article
- Analysis of existence of multidrug-resistant H58 gene inNew microbes and new infections · 2020Article
- Gallbladder carriage generates genetic variation and genome degradation in Salmonella Typhi.PLoS pathogens · 2020Article
- Population structure and transmission modes of indigenous typhoid in Taiwan.BMC medical genomics · 2019Article
- Polymorphism analysis of the apxIA gene of Actinobacillus pleuropneumoniae serovar 5 isolated in swine herds from Brazil.PloS one · 2018Article
- Antimicrobial Resistance ofInternational journal of microbiology · 2017Article
- An extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid.Nature communications · 2016Article
- The Molecular and Spatial Epidemiology of Typhoid Fever in Rural Cambodia.PLoS neglected tropical diseases · 2016Article
- Identification and Characterization of a GeneFrontiers in cellular and infection microbiology · 2016Article
- Twenty years of bacterial genome sequencing.Nature reviews. Microbiology · 2015Review
- Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events.Nature genetics · 2015Article
- The Hd, Hj, and Hz66 flagella variants of Salmonella enterica serovar Typhi modify host responses and cellular interactions.Scientific reports · 2015Article
- Antimicrobial resistance in Salmonella enterica Serovar Typhi isolates from Bangladesh, Indonesia, Taiwan, and Vietnam.Antimicrobial agents and chemotherapy · 2014Article
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
High-throughput epidemiological typing systems that provide phylogenetic and genotypic information are beneficial for tracking bacterial pathogens in the field. The incidence of Salmonella enterica serovar Typhi infection in Indonesia is high and is associated with atypical phenotypic traits such as expression of the j and the z66 flagellum antigens. Utilizing a high-throughput genotyping platform to investigate known nucleotide polymorphisms dispersed around the genome, we determined the haplotypes of 140 serovar Typhi isolates associated with Indonesia. We identified nine distinct serovar Typhi haplotypes circulating in Indonesia for more than 30 years, with eight of these present in a single Jakarta suburb within a 2-year period. One dominant haplotype, H59, is associated with j and z66 flagellum expression, representing a potential pathotype unique to Indonesia. Phylogenetic analysis suggests that H59 z66(+), j(+) isolates emerged relatively recently in terms of the origin of serovar Typhi and are geographically restricted. These data demonstrate the potential of high-throughput genotyping platforms for analyzing serovar Typhi populations in the field. The study also provides insight into the evolution of serovar Typhi and demonstrates the value of a molecular epidemiological technique that is exchangeable, that is internet friendly, and that has global utility.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.