Evidence map›Paper›PMID 18322035›Full record

ReviewMicrobiology and molecular biology reviews : MMBR2008

Molecular control of bacterial death and lysis.

Kelly C Rice, Kenneth W Bayles

Open access · greenAbstract readReview
In one paragraph

Review in Microbiology and molecular biology reviews : MMBR, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 186 papers.

0numbers the graph read from it
0cells of the map it votes in
186citing papers in PubMed
8.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

186 citing papers in PubMed, 364 citations in OpenAlex.

  1. Polyethyleneimine nanoparticles incorporated into resin composite cause cell death and trigger biofilm stress in vivo.Proceedings of the National Academy of Sciences of the United States of America · 2010
    Trial
  2. Review
  3. Review
  4. Review
  5. Article
  6. Mechanistic study on the susceptibility ofApplied and environmental microbiology · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Characterization of MreCD inJournal of oral microbiology · 2025
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. FASEB bioAdvances · 2023
    Article

126 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kelly C RiceDepartment of Microbiology and Pathology, University of Nebraska Medical Center, 668 S. 41st St., PYH4014, Omaha, NE 68198-6245, USA.
Kenneth W Bayles
University of Nebraska Medical Center · US

Funding

The molecular control of bacterial autolysisR01AI038901 · NIAID · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BAYLES, KENNETH W. · 2003 to 2012
$3.1M
NIAID NIH HHS R01 AI038901NIAID NIH HHS R01AI038901
6 · The paper itself

Abstract

Although the phenomenon of bacterial cell death and lysis has been studied for over 100 years, the contribution of these important processes to bacterial physiology and development has only recently been recognized. Contemporary study of cell death and lysis in a number of different bacteria has revealed that these processes, once thought of as being passive and unregulated, are actually governed by highly complex regulatory systems. An emerging paradigm in this field suggests that, analogous to programmed cell death in eukaryotes, regulated cell death and lysis in bacteria play an important role in both developmental processes, such as competence and biofilm development, and the elimination of damaged cells, such as those irreversibly injured by environmental or antibiotic stress. Further study in this exciting field of bacterial research may provide new insight into the potential evolutionary link between control of cell death in bacteria and programmed cell death (apoptosis) in eukaryotes.

Indexed as

ApoptosisBacteriaBacteriolysisBacterial ToxinsCannibalismBacterial Toxins

Identifiers

PMID18322035
PMCPMC2268280
OpenAlexW2128139766

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.