Evidence map›Paper›PMID 18322011›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2008

Does antisense make sense of AID targeting?

Sergio Roa, Fei Li Kuang, Matthew D Scharff

Abstract readComment
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Regulatory roles of natural antisense transcripts.Nature reviews. Molecular cell biology · 2009
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Sergio RoaDepartment of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Fei Li Kuang
Matthew D Scharff

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007288 · NIGMS · YESHIVA UNIVERSITY · PI AKABAS, MYLES H. · 1985 to 2022
$35.6M
SOMATIC MUTATION OF IG VARIABLE REGIONSR01CA072649 · NCI · YESHIVA UNIVERSITY · PI SCHARFF, MATTHEW D · 1997 to 2014
$5.0M
Mismatch repair in V region mutation and isotype switchingR01CA102705 · NCI · YESHIVA UNIVERSITY · PI SCHARFF, MATTHEW D · 2003 to 2013
$3.2M
NCI NIH HHS R01 CA072649NCI NIH HHS R01 CA102705NCI NIH HHS R01CA102705NCI NIH HHS R01CA72649NIGMS NIH HHS T32 GM 007288NIGMS NIH HHS T32 GM007288
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AICDA (Activation-Induced Cytidine Deaminase)AnimalsCytidine DeaminaseGenes, Immunoglobulin Heavy ChainImmunoglobulin Class SwitchingImmunoglobulin Heavy ChainsImmunoglobulin Variable RegionMiceRNA, AntisenseSomatic Hypermutation, ImmunoglobulinVDJ ExonsAICDA (Activation-Induced Cytidine Deaminase)Cytidine DeaminaseImmunoglobulin Heavy ChainsImmunoglobulin Variable RegionRNA, Antisense

Identifiers

PMID18322011
PMCPMC2268770

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.