ArticlePsychoneuroendocrinology2008
Effects of gender and cigarette smoking on reactivity to psychological and pharmacological stress provocation.
Article in Psychoneuroendocrinology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 77 citations in OpenAlex.
- The influence of gender and oxytocin on stress reactivity, cigarette craving, and smoking in a randomized, placebo-controlled laboratory relapse paradigm.Psychopharmacology · 2020Trial
- Differences in mood and cortisol by menstrual phase during acute smoking abstinence: A within-subject comparison.Experimental and clinical psychopharmacology · 2017Trial
- Timing of nicotine lozenge administration to minimize trigger induced craving and withdrawal symptoms.Addictive behaviors · 2017Trial
- Stress decreases the ability to resist smoking and potentiates smoking intensity and reward.Journal of psychopharmacology (Oxford, England) · 2011Trial
- Patterns of cortisol and craving by menstrual phase in women attempting to quit smoking.Addictive behaviors · 2009Trial
- Mindfulness training and stress reactivity in substance abuse: results from a randomized, controlled stage I pilot study.Substance abuseTrial
- Uncertain Drop vs. Socially Evaluated Cold Pressor: Uncertain Stress Elicits Stronger Psychophysiological Responses and Differential Neural Oscillatory Patterns.Brain sciences · 2026Article
- Neuroendocrine contribution to sex-related variations in adverse air pollution health effects.Journal of toxicology and environmental health. Part B, Critical reviews · 2024Review
- Therapeutics for Substance-Using Women: The Need to Elucidate Sex-Specific Targets for Better-Tailored Treatments.Handbook of experimental pharmacology · 2023Article
- Blunted cortisol and normal sympathetic nervous system responses to an acute psychosocial stressor in internet addiction.Heliyon · 2022Article
- Smokers show an altered hemodynamic profile to active stress: Evidence of a dysregulated stress response in young adults.Psychophysiology · 2022Article
- Ahi1 regulates serotonin production by the GR/ERβ/TPH2 pathway involving sexual differences in depressive behaviors.Cell communication and signaling : CCS · 2022Article
- Responses to social evaluative stress in regular cannabis smokers.Journal of psychopharmacology (Oxford, England) · 2021Article
- Association between heaviness of cigarette smoking and serious psychological distress is stronger in women than in men: a nationally representative cross-sectional survey in Japan.Harm reduction journal · 2021Article
- The Impact of Smoking on Clinical Outcomes after Percutaneous Coronary Intervention in Women Compared to Men.Journal of interventional cardiology · 2021Article
- A Gender Perspective of Addictive Disorders.Current addiction reports · 2021Review
- Examining sex, adverse childhood experiences, and oxytocin on neuroendocrine reactivity in smokers.Psychoneuroendocrinology · 2020Article
- Effect of sex differences in remifentanil requirements for inhibiting the response to a COBMC anesthesiology · 2020Article
- Addressing Health Challenges of Women Across the Life Course: Summary of the Women's Health 2018 Preconference Symposium.Journal of women's health (2002) · 2019Article
- Gender differences in subjective stress and neuroendocrine response to a stress task among individuals with opioid dependence: A pilot study.Addictive behaviors · 2019Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
Abstract
We examined the influence of gender and smoking status on reactivity in two human laboratory stress paradigms. Participants were 46 (21 men, 25 women) healthy individuals who completed the Trier Social Stress Task (i.e., performed speech and math calculations in front of an audience) and a pharmacological stress provocation (i.e., administration of corticotrophin releasing hormone (CRH)) after an overnight hospital stay. Approximately half (53%) of the participants were smokers. Cortisol, adrenocorticotrophin hormone (ACTH), physiologic measures (heart rate, blood pressure), and subjective stress were assessed at baseline and at several time points post-task. Men demonstrated higher baseline ACTH and blood pressure as compared to women; however, ACTH and blood pressure responses were more pronounced in women. Women smokers evidenced a more blunted cortisol response as compared to non-smoking women, whereas smoking status did not affect the cortisol response in men. Finally, there was a more robust cardiovascular and subjective response to the Trier as compared to the CRH. Although preliminary, the findings suggest that women may be more sensitive than men to the impact of cigarette smoking on cortisol response. In addition, there is some evidence for a more robust neuroendocrine and physiologic response to acute laboratory stress in women as compared to men.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.