ReviewPflugers Archiv : European journal of physiology2009
Vacuolar H(+)-ATPase-an enzyme for all seasons.
Review in Pflugers Archiv : European journal of physiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 74 citations in OpenAlex.
- Exploring the potential use of Chinese herbs in regulating the inflammatory microenvironment of tumours based on the concept of 'state-target identification and treatment': a scooping review.Chinese medicine · 2023Review
- The Toxoplasma plant-like vacuolar compartment (PLVAC).The Journal of eukaryotic microbiology · 2022Review
- Fully Automated Computational Approach for Precisely Measuring Organelle Acidification with Optical pH Sensors.ACS applied materials & interfaces · 2022Article
- SCAMP5 plays a critical role in axonal trafficking and synaptic localization of NHE6 to adjust quantal size at glutamatergic synapses.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Regulation and function of V-ATPases in physiology and disease.Biochimica et biophysica acta. Biomembranes · 2020Review
- The Toxoplasma Vacuolar HCell reports · 2019Article
- NaThe Journal of physiology · 2017Article
- Disorders of lysosomal acidification-The emerging role of v-ATPase in aging and neurodegenerative disease.Ageing research reviews · 2016Review
- Determinants of Glycosaminoglycan (GAG) Structure.Biomolecules · 2015Review
- Death Associated Protein Kinase (DAPK) -mediated neurodegenerative mechanisms in nematode excitotoxicity.BMC neuroscience · 2015Article
- Crystal structure of subunits D and F in complex gives insight into energy transmission of the eukaryotic V-ATPase from Saccharomyces cerevisiae.The Journal of biological chemistry · 2015Article
- Slc26a11 is prominently expressed in the brain and functions as a chloride channel: expression in Purkinje cells and stimulation of V H⁺-ATPase.Pflugers Archiv : European journal of physiology · 2013Article
- Crystal and NMR structures give insights into the role and dynamics of subunit F of the eukaryotic V-ATPase from Saccharomyces cerevisiae.The Journal of biological chemistry · 2013Article
- Unconventional chemiosmotic coupling of NHA2, a mammalian Na+/H+ antiporter, to a plasma membrane H+ gradient.The Journal of biological chemistry · 2012Article
- Crystallization and preliminary X-ray crystallographic analysis of subunit F (F(1-94)), an essential coupling subunit of the eukaryotic V(1)V(O)-ATPase from Saccharomyces cerevisiae.Acta crystallographica. Section F, Structural biology and crystallization communications · 2012Article
- Osteopetrosis mutation R444L causes endoplasmic reticulum retention and misprocessing of vacuolar H+-ATPase a3 subunit.The Journal of biological chemistry · 2012Article
- Mutations in vacuolar H+ -ATPase subunits lead to biliary developmental defects in zebrafish.Developmental biology · 2012Article
- Rational identification of enoxacin as a novel V-ATPase-directed osteoclast inhibitor.Current protein & peptide science · 2012Review
- Article
- H(+)-coupled divalent metal-ion transporter-1: functional properties, physiological roles and therapeutics.Current topics in membranes · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The life of every eukaryotic cell depends on the function of vacuolar H(+)-ATPase (V-ATPase). Because of its complexity and its challenging properties, the study of this enzyme has lagged behind that of its close relative, F-ATPase. We now know that V-ATPase is vital for many more physiological and biochemical processes than anticipated when the enzyme was discovered a few decades ago. It plays a crucial role in the proper functioning of internal organelles such as vacuoles, lysosomes, synaptic vesicles, endosomes, secretory granules, and the Golgi apparatus as well as in plasma membrane of several organisms and specific tissues and specialized cells. Knowledge of its involvement in several diseases, including cancer, has helped to establish the importance of V-ATPase for the preservation of life.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.