Evidence map›Paper›PMID 18320152›Full record

ReviewSeminars in immunopathology2008

In vivo imaging of the immune response in the eye.

Doran B Spencer, Ellen J Lee, Tatsushi Kawaguchi, James T Rosenbaum

Abstract readReview
PubMed Publisher
In one paragraph

Review in Seminars in immunopathology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. In vivo imaging of therapy-induced anti-cancer immune responses in humans.Cellular and molecular life sciences : CMLS · 2013
    Review
  3. In vivo molecular imaging in retinal disease.Journal of ophthalmology · 2012
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Doran B SpencerDepartment of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR 97239, USA.
Ellen J Lee
Tatsushi Kawaguchi
James T Rosenbaum

Funding

FOUR DIMENTIONAL IMAGING OF THE IMMUNE RESPONSE IN VIVOR01EY013093 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI ROSENBAUM, JAMES T · 1999 to 2010
$5.0M
In vivo imaging of corneal inflammationK08EY015448 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEE, ELLEN J · 2004 to 2008
$554k
NEI NIH HHS EY006484NEI NIH HHS EY013093NEI NIH HHS EY015448
6 · The paper itself

Abstract

The immune system is governed by dynamic events involving in part direct intercellular interactions between an immune cell and other cells or the cell's environment. Owing to its unique optical characteristics, the eye offers remarkable opportunities for the analysis of the immune system by intravital microscopy. In this review, we present a brief overview of the current state of knowledge of leukocyte trafficking in each of three anatomically distinct and medically important regions of the eye (cornea, iris, retina) as determined by the application of intravital microscopy to animal models of disease. Additionally, we discuss the use of ocular imaging in patients and volunteers. Finally, we examine the future prospects for this field in terms of its potential for impacting our understanding of fundamental immunological phenomena.

Indexed as

AnimalsChemotaxis, LeukocyteDiagnostic ImagingEyeHumansMicroscopy, Video

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.