ReviewInternal and emergency medicine2008
The conundrum of hyperuricemia, metabolic syndrome, and renal disease.
Review in Internal and emergency medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 55 citations in OpenAlex.
- Hyperuricemia and metabolic syndrome in type 2 diabetes mellitus patients at Hawassa university comprehensive specialized hospital, South West Ethiopia.BMC endocrine disorders · 2017Trial
- Triglyceride-glucose index and its additive interaction withAnnals of medicine · 2024Article
- Vitamin D pathway gene variation rs3740165 is associated with serological uric acid levels in healthy Chinese women.Frontiers in endocrinology · 2022Article
- Hyperuricemia and Progression of Chronic Kidney Disease: A Review from Physiology and Pathogenesis to the Role of Urate-Lowering Therapy.Diagnostics (Basel, Switzerland) · 2021Review
- LncRNA-HOTAIR promotes endothelial cell pyroptosis by regulating the miR-22/NLRP3 axis in hyperuricaemia.Journal of cellular and molecular medicine · 2021Article
- 27-Hydroxycholesterol regulates human SLC22A12 gene expression through estrogen receptor action.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021Article
- Association between hyperuricemia and glycated hemoglobin in type 2 diabetes at the District Hospital of Dschang.The Pan African medical journal · 2021Article
- Associations of Triglyceride-Glucose Index and Its Derivatives with Hyperuricemia Risk: A Cohort Study in Chinese General Population.International journal of endocrinology · 2020Article
- Xanthine oxidase inhibitors in elderly patients with heart failure: useful or useless?Internal and emergency medicine · 2019Article
- Renoprotective effect of topiroxostat via antioxidant activity in puromycin aminonucleoside nephrosis rats.Physiological reports · 2017Article
- Serum Uric Acid Relation for Hearing Threshold Shift.Clinical and experimental otorhinolaryngology · 2017Article
- Relationship between serum uric Acid and bone mineral density in the general population and in rats with experimental hyperuricemia.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2015Article
- Hyperuricemia: An Early Marker for Severity of Illness in Sepsis.International journal of nephrology · 2015Article
- CKD of unknown origin in Central America: the case for a Mesoamerican nephropathy.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2014Review
- Alopecia universalis, renal stones, and hyperuricemia: a familial or an unfamiliar association.Journal of family medicine and primary care · 2014Article
- Cross-sectional and longitudinal associations between serum uric acid and metabolic syndrome.Endocrine · 2012Article
- Salivary uric acid as a noninvasive biomarker of metabolic syndrome.Diabetology & metabolic syndrome · 2012Article
- Uric acid: a starring role in the intricate scenario of metabolic syndrome with cardio-renal damage?Internal and emergency medicine · 2012Review
- The relationship between serum levels of uric acid and prognosis of infection in critically ill patients.World journal of emergency medicine · 2012Article
- Hyperuricemia and metabolic syndrome: associations with chronic kidney disease.Clinical rheumatology · 2011Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
The level of serum uric acid in human has been increasing over the last decades, and correlates with an increase prevalence of renal disease and metabolic syndrome. Understanding the role of uric acid in these conditions may provide clues for preventing the current epidemic of renal disease. Controversy still remains if hyperuricemia is simply a consequence or a cause of renal disease although epidemiological studies have attempted to resolve this issue. In this review, we discuss the clinical and experimental evidence for a causal role of hyperuricemia in renal diseases and potential relationships of hyperuricemia with metabolic syndrome.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.