ArticleProceedings of the National Academy of Sciences of the United States of America2008
Simultaneous in vivo positron emission tomography and magnetic resonance imaging.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
89 citing papers in PubMed, 264 citations in OpenAlex.
- The Impact of PET Imaging on Translational Medicine: Insights from Large-Animal Disease Models.Biomolecules · 2025Review
- Silicon photomultiplier signal readout and multiplexing techniques for positron emission tomography: a review.Biomedical engineering letters · 2022Review
- Modern Diagnostic Imaging Technique Applications and Risk Factors in the Medical Field: A Review.BioMed research international · 2022Review
- Performance Evaluation of SimPET-X, a PET Insert for Simultaneous Mouse Total-Body PET/MR Imaging.Molecular imaging and biology · 2021Article
- Photoacoustic computed tomography for functional human brain imaging [Invited].Biomedical optics express · 2021Review
- Quantitative Rodent Brain Receptor Imaging.Molecular imaging and biology · 2020Review
- PET and SPECT imaging of the brain: a review on the current status of nuclear medicine in Japan.Japanese journal of radiology · 2020Review
- Radiolabeled PET/MRI Nanoparticles for Tumor Imaging.Journal of clinical medicine · 2019Review
- Direct attenuation correction of brain PET images using only emission data via a deep convolutional encoder-decoder (Deep-DAC).European radiology · 2019Article
- Screening for Dementia Caused by Modifiable Lifestyle Choices Using Hybrid PET/MRI.Journal of Alzheimer's disease reports · 2019Review
- Performance evaluation of RF coils integrated with an RF-penetrable PET insert for simultaneous PET/MRI.Magnetic resonance in medicine · 2019Article
- Functional probes for cardiovascular molecular imaging.Quantitative imaging in medicine and surgery · 2018Review
- Neuroinflammation and Cytokines in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Critical Review of Research Methods.Frontiers in neurology · 2018Review
- Estimation of subject coregistration errors during multimodal preclinical imaging using separate instruments: origins and avoidance of artifacts.Journal of medical imaging (Bellingham, Wash.) · 2017Article
- Principles of Simultaneous PET/MR Imaging.Magnetic resonance imaging clinics of North America · 2017Review
- Simultaneous PET/MRI with (13)C magnetic resonance spectroscopic imaging (hyperPET): phantom-based evaluation of PET quantification.EJNMMI physics · 2016Article
- Anatomically-aided PET reconstruction using the kernel method.Physics in medicine and biology · 2016Article
- FPGA-based RF interference reduction techniques for simultaneous PET-MRI.Physics in medicine and biology · 2016Article
- Simultaneous PET/MRI Imaging During Mouse Cerebral Hypoxia-ischemia.Journal of visualized experiments : JoVE · 2015Article
- A 31-channel MR brain array coil compatible with positron emission tomography.Magnetic resonance in medicine · 2015Article
29 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
Positron emission tomography (PET) and magnetic resonance imaging (MRI) are widely used in vivo imaging technologies with both clinical and biomedical research applications. The strengths of MRI include high-resolution, high-contrast morphologic imaging of soft tissues; the ability to image physiologic parameters such as diffusion and changes in oxygenation level resulting from neuronal stimulation; and the measurement of metabolites using chemical shift imaging. PET images the distribution of biologically targeted radiotracers with high sensitivity, but images generally lack anatomic context and are of lower spatial resolution. Integration of these technologies permits the acquisition of temporally correlated data showing the distribution of PET radiotracers and MRI contrast agents or MR-detectable metabolites, with registration to the underlying anatomy. An MRI-compatible PET scanner has been built for biomedical research applications that allows data from both modalities to be acquired simultaneously. Experiments demonstrate no effect of the MRI system on the spatial resolution of the PET system and <10% reduction in the fraction of radioactive decay events detected by the PET scanner inside the MRI. The signal-to-noise ratio and uniformity of the MR images, with the exception of one particular pulse sequence, were little affected by the presence of the PET scanner. In vivo simultaneous PET and MRI studies were performed in mice. Proof-of-principle in vivo MR spectroscopy and functional MRI experiments were also demonstrated with the combined scanner.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.