ArticlePLoS biology2008
Functional adaptation of a plant receptor-kinase paved the way for the evolution of intracellular root symbioses with bacteria.
Article in PLoS biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed.
- Integrated multi-omics decipher the complex nodule microbiota and distinct Frankiaceae symbiotic traits in wild actinorhizal plants.The New phytologist · 2026Article
- Review
- A novel cis-element enabled bacterial uptake by plant cells.Nature plants · 2026Article
- Shedding light on receptor kinase processing.PLoS pathogens · 2025Article
- Pangenome analysis provides insights into legume evolution and breeding.Nature genetics · 2025Article
- A rare non-canonical splice site in Trema orientalis SYMRK does not affect its dual symbiotic functioning in endomycorrhiza and rhizobium nodulation.BMC plant biology · 2023Article
- Root structure syndromes of four families of monocots in the Middle Urals.Plant diversity · 2023Article
- Article
- Review
- Legume NCRs and nodule-specific defensins of actinorhizal plants-Do they share a common origin?PloS one · 2022Article
- Hairy CRISPR: Genome Editing in Plants Using Hairy Root Transformation.Plants (Basel, Switzerland) · 2021Review
- Malectin/Malectin-like domain-containing proteins: A repertoire of cell surface molecules with broad functional potential.Cell surface (Amsterdam, Netherlands) · 2021Review
- Symbiotic Regulatory Genes Controlling Nodule Development inPlants (Basel, Switzerland) · 2020Review
- Cell Communications among Microorganisms, Plants, and Animals: Origin, Evolution, and Interplays.International journal of molecular sciences · 2020Review
- The study of host-microbiome (co)evolution across levels of selection.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Article
- A Roadmap toward Engineered Nitrogen-Fixing Nodule Symbiosis.Plant communications · 2020Review
- Gene Expression in Nitrogen-Fixing Symbiotic Nodule Cells inThe Plant cell · 2020Review
- The Evolutionary Aspects of Legume Nitrogen-Fixing Nodule Symbiosis.Results and problems in cell differentiation · 2020Article
- Frankia-Enriched Metagenomes from the Earliest Diverging Symbiotic Frankia Cluster: They Come in Teams.Genome biology and evolution · 2019Article
- A set of Arabidopsis genes involved in the accommodation of the downy mildew pathogen Hyaloperonospora arabidopsidis.PLoS pathogens · 2019Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nitrogen-fixing root nodule symbioses (RNS) occur in two major forms-Actinorhiza and legume-rhizobium symbiosis-which differ in bacterial partner, intracellular infection pattern, and morphogenesis. The phylogenetic restriction of nodulation to eurosid angiosperms indicates a common and recent evolutionary invention, but the molecular steps involved are still obscure. In legumes, at least seven genes-including the symbiosis receptor-kinase gene SYMRK-are essential for the interaction with rhizobia bacteria and for the Arbuscular Mycorrhiza (AM) symbiosis with phosphate-acquiring fungi, which is widespread in occurrence and believed to date back to the earliest land plants. We show that SYMRK is also required for Actinorhiza symbiosis of the cucurbit Datisca glomerata with actinobacteria of the genus Frankia, revealing a common genetic basis for both forms of RNS. We found that SYMRK exists in at least three different structural versions, of which the shorter forms from rice and tomato are sufficient for AM, but not for functional endosymbiosis with bacteria in the legume Lotus japonicus. Our data support the idea that SYMRK sequence evolution was involved in the recruitment of a pre-existing signalling network from AM, paving the way for the evolution of intracellular root symbioses with nitrogen-fixing bacteria.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.