ReviewClinical & developmental immunology2007
Blurring borders: innate immunity with adaptive features.
Review in Clinical & developmental immunology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Innate receptors modulating adaptive T cell responses: KIR-HLA interactions and T cell-mediated control of chronic viral infections.Immunogenetics · 2023Review
- Is chimerism associated with cancer across the tree of life?PloS one · 2023Article
- Tick Immunobiology and Extracellular Traps: An Integrative Vision to Control of Vectors.Pathogens (Basel, Switzerland) · 2021Review
- Phenotypic and Functional Characteristics of a Novel Influenza Virus Hemagglutinin-Specific Memory NK Cell.Journal of virology · 2021Article
- Healthspan pathway maps inAging · 2020Review
- A fruit diet rather than invertebrate diet maintains a robust innate immunity in an omnivorous tropical songbird.The Journal of animal ecology · 2020Article
- Commentary: Blurring Borders: Innate Immunity with Adaptive Features.Frontiers in microbiology · 2016Article
- Immune-directed support of rich microbial communities in the gut has ancient roots.Developmental and comparative immunology · 2014Review
- Corals and their potential applications to integrative medicine.Evidence-based complementary and alternative medicine : eCAM · 2014Article
- Origin of innate immune responses: revelation of food and medicinal applications.Journal of traditional and complementary medicine · 2013Review
- Evolution of B cell immunity.Annual review of animal biosciences · 2013Review
- Changing views of the evolution of immunity.Frontiers in immunology · 2013Article
- Drosophila at the intersection of infection, inflammation, and cancer.Frontiers in cellular and infection microbiology · 2013Review
- Effects of environmental change on wildlife health.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2009Review
- A feeding induced switch from a variable to a homogenous state of the earthworm gut microbiota within a host population.PloS one · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adaptive immunity has often been considered the penultimate of immune capacities. That system is now being deconstructed to encompass less stringent rules that govern its initiation, actual effector activity, and ambivalent results. Expanding the repertoire of innate immunity found in all invertebrates has greatly facilitated the relaxation of convictions concerning what actually constitutes innate and adaptive immunity. Two animal models, incidentally not on the line of chordate evolution (C. elegans and Drosophila), have contributed enormously to defining homology. The characteristics of specificity and memory and whether the antigen is pathogenic or nonpathogenic reveal considerable information on homology, thus deconstructing the more fundamentalist view. Senescence, cancer, and immunosuppression often associated with mammals that possess both innate and adaptive immunity also exist in invertebrates that only possess innate immunity. Strict definitions become blurred casting skepticism on the utility of creating rigid definitions of what innate and adaptive immunity are without considering overlaps.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.