ReviewAlzheimer disease and associated disorders
Children of persons with Alzheimer disease: what does the future hold?
Review in Alzheimer disease and associated disorders. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02384993 (Aerobic Exercise for Alzheimer's Disease Prevention in At-Risk Middle-Aged Adults), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Aerobic Exercise for Alzheimer's Disease Prevention in At-Risk Middle-Aged Adults
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Genetic counseling and testing for Alzheimer disease: joint practice guidelines of the American College of Medical Genetics and the National Society of Genetic Counselors.Genetics in medicine : official journal of the American College of Medical Genetics · 2011Guideline
- Community memory screening as a strategy for recruiting older adults into Alzheimer's disease research.Alzheimer's research & therapy · 2020Article
- Protocol of Aerobic Exercise and Cognitive Health (REACH): A Pilot Study.Journal of Alzheimer's disease reports · 2020Article
- Early-Onset Alzheimer Disease.Neurologic clinics · 2017Review
- Family History of Alzheimer's Disease is Associated with Impaired Perceptual Discrimination of Novel Objects.Journal of Alzheimer's disease : JAD · 2017Article
- Linear Regression with a Randomly Censored Covariate: Application to an Alzheimer's Study.Journal of the Royal Statistical Society. Series C, Applied statistics · 2017Article
- Maternal dementia age at onset in relation to amyloid burden in non-demented elderly offspring.Neurobiology of aging · 2016Article
- The Utility of Cerebral Blood Flow as a Biomarker of Preclinical Alzheimer's Disease.Cellular and molecular neurobiology · 2016Review
- A diffusion model analysis of episodic recognition in preclinical individuals with a family history for Alzheimer's disease: The adult children study.Neuropsychology · 2016Article
- Multiple Imputation of a Randomly Censored Covariate Improves Logistic Regression Analysis.Journal of applied statistics · 2016Article
- Subjective memory complaints, cortical thinning, and cognitive dysfunction in middle-aged adults at risk for AD.Alzheimer's & dementia (Amsterdam, Netherlands) · 2015Article
- Cerebral blood flow is diminished in asymptomatic middle-aged adults with maternal history of Alzheimer's disease.Cerebral cortex (New York, N.Y. : 1991) · 2014Article
- Cerebral blood flow measured by arterial spin labeling MRI as a preclinical marker of Alzheimer's disease.Journal of Alzheimer's disease : JAD · 2014Review
- Cognitive activities and cognitive performance in middle-aged adults at risk for Alzheimer's disease.Psychology and aging · 2013Article
- Influence of Alzheimer disease family history and genetic risk on cognitive performance in healthy middle-aged and older people.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2012Article
- Machine learning amplifies the effect of parental family history of Alzheimer's disease on list learning strategy.Journal of the International Neuropsychological Society : JINS · 2012Article
- Latent structure and factorial invariance of a neuropsychological test battery for the study of preclinical Alzheimer's disease.Neuropsychology · 2010Article
- Apolipoprotein-E genotype and human immunodeficiency virus-associated neurocognitive disorder: the modulating effects of older age and disease severity.Neurobehavioral HIV medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 10 institutions in 1 country.
Funding
Abstract
Children of persons with Alzheimer disease (AD), as a group, face an increased risk of developing AD. Many of them, throughout their adult lives, seek input on how to reduce their chances of one day suffering their parent's fate. We examine the state of knowledge with respect to risk and protective factors for AD and recommend a research agenda with special emphasis on AD offspring.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.