ArticleBMC bioinformatics2008
SNP@Promoter: a database of human SNPs (single nucleotide polymorphisms) within the putative promoter regions.
Article in BMC bioinformatics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 55 citations in OpenAlex.
- Predicting heterosisFrontiers in plant science · 2023Article
- Variation in the Promoter Region of theInternational journal of molecular sciences · 2019Article
- Architecture of polymorphisms in the human genome reveals functionally important and positively selected variants in immune response and drug transporter genes.Human genomics · 2018Article
- VEGF +936 C/T Genetic Polymorphism in Patients with Cervical Dysplasia.Analytical cellular pathology (Amsterdam) · 2016Article
- Association of Nicotinamide Phosphoribosyltransferase (NAMPT) Gene Polymorphisms and of Serum NAMPT Levels with Dilated Cardiomyopathy in a Chinese Population.International journal of molecular sciences · 2015Article
- Human Genes Encoding Transcription Factors and Chromatin-Modifying Proteins Have Low Levels of Promoter Polymorphism: A Study of 1000 Genomes Project Data.International journal of genomics · 2015Article
- Polymorphisms in poly (ADP-ribose) polymerase-1 (PARP1) promoter and 3' untranslated region and their association with PARP1 expression in breast cancer patients.International journal of clinical and experimental pathology · 2015Article
- Association of interleukin-10 gene promoter polymorphisms with susceptibility to acute pyelonephritis in children.Folia microbiologica · 2014Article
- rSNPBase: a database for curated regulatory SNPs.Nucleic acids research · 2014Article
- Article
- Genetic basis of olfactory cognition: extremely high level of DNA sequence polymorphism in promoter regions of the human olfactory receptor genes revealed using the 1000 Genomes Project dataset.Frontiers in psychology · 2014Article
- Significance of rs1271572 in the estrogen receptor beta gene promoter and its correlation with breast cancer in a southwestern Chinese population.Journal of biomedical science · 2013Article
- Mutations and binding sites of human transcription factors.Frontiers in genetics · 2012Article
- A fast and accurate SNP detection algorithm for next-generation sequencing data.Nature communications · 2012Article
- Associations among types of impulsivity, substance use problems and neurexin-3 polymorphisms.Drug and alcohol dependence · 2011Article
- Prediction of functional regulatory SNPs in monogenic and complex disease.Human mutation · 2011Article
- dPORE-miRNA: polymorphic regulation of microRNA genes.PloS one · 2011Article
- Article
- NovelSNPer: A Fast Tool for the Identification and Characterization of Novel SNPs and InDels.Advances in bioinformatics · 2011Article
- Bioinformatic tools for identifying disease gene and SNP candidates.Methods in molecular biology (Clifton, N.J.) · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnalysis of single nucleotide polymorphism (SNP) is becoming a key research in genomics fields. Many functional analyses of SNPs have been carried out for coding regions and splicing sites that can alter proteins and mRNA splicing. However, SNPs in non-coding regulatory regions can also influence important biological regulation. Presently, there are few databases for SNPs in non-coding regulatory regions. DESCRIPTION: We identified 488,452 human SNPs in the putative promoter regions that extended from the +5000 bp to -500 bp region of the transcription start sites. Some SNPs occurring in transcription factor (TF) binding sites were also predicted (47,832 SNP; 9.8%). The result is stored in a database: SNP@promoter. Users can search the SNP@Promoter database using three entries: 1) by SNP identifier (rs number from dbSNP), 2) by gene (gene name, gene symbol, refSeq ID), and 3) by disease term. The SNP@Promoter database provides extensive genetic information and graphical views of queried terms.
conclusionWe present the SNP@Promoter database. It was created in order to predict functional SNPs in putative promoter regions and predicted transcription factor binding sites. SNP@Promoter will help researchers to identify functional SNPs in non-coding regions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.