Evidence map›Paper›PMID 18313763›Full record

ReviewVeterinary immunology and immunopathology2008

Avian defensins.

Albert van Dijk, Edwin J A Veldhuizen, Henk P Haagsman

Abstract readReview
In one paragraph

Review in Veterinary immunology and immunopathology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 189 citations in OpenAlex.

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  14. Review
  15. Effects ofFrontiers in physiology · 2023
    Article
  16. Article
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  19. Article
  20. Antimicrobial Peptides: An Update on Classifications and Databases.International journal of molecular sciences · 2021
    Review

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Albert van DijkDepartment of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, PO Box 80.175, 3508 TD Utrecht, The Netherlands.
Edwin J A Veldhuizen
Henk P Haagsman
Utrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modulation of defensin expression may be one way to improve animal health and to reduce zoonotic diseases. Defensins are small, cationic, and amphipathic cysteine-rich antibiotic peptides found in plants, insects, mammals and birds. Whereas alpha- and theta-defensins appear to be absent in birds, several beta-defensins have been isolated from avian heterophils. In addition, beta-defensins were found to be constitutively or inducibly expressed at mucosal surfaces of the respiratory, intestinal and urogenital tracts. In this review the current knowledge of the defensin repertoire of birds, their tissue-specific expression, regulation and corresponding biological functions are described.

Indexed as

Animalsbeta-DefensinsBird DiseasesBirdsCommunicable DiseasesZoonosesbeta-Defensins

Identifiers

PMID18313763
PMCPMC7112556
OpenAlexW4205323869

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.