SynthesisLancet (London, England)2008
Complex interventions to improve physical function and maintain independent living in elderly people: a systematic review and meta-analysis.
Synthesis in Lancet (London, England), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 276 papers, 18 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
276 citing papers in PubMed, 18 syntheses or guidelines pooled it, 783 citations in OpenAlex.
- The effectiveness of alternatives to residential care for older people with on-going health and social care needs: a systematic review.BMC geriatrics · 2026Pooled it
- Home-Based Comprehensive Geriatric Assessment for Community-Dwelling, At-Risk, Frail Older Adults: A Systematic Review and Meta-Analysis.Journal of the American Geriatrics Society · 2025Pooled it
- Community-based complex interventions to sustain independence in older people, stratified by frailty: a systematic review and network meta-analysis.Health technology assessment (Winchester, England) · 2024Pooled it
- Community based complex interventions to sustain independence in older people: systematic review and network meta-analysis.BMJ (Clinical research ed.) · 2024Pooled it
- Effectiveness of fall prevention interventions in residential aged care and community settings: an umbrella review.BMC geriatrics · 2024Pooled it
- Pooled it
- Comprehensive Geriatric Assessment for community-dwelling, high-risk, frail, older people.The Cochrane database of systematic reviews · 2022Pooled it
- Effective Interventions on Improving Elderly's Independence in Activity of Daily Living: A Systematic Review and Logic Model.Frontiers in public health · 2020Pooled it
- The evidence for services to avoid or delay residential aged care admission: a systematic review.BMC geriatrics · 2019Pooled it
- What are the most effective interventions to improve physical performance in pre-frail and frail adults? A systematic review of randomised control trials.BMC geriatrics · 2019Pooled it
- Disparities in the Prevalence and Correlates of Disability in Older Immigrants in the USA: a Systematic Review of the Literature.Journal of racial and ethnic health disparities · 2019Pooled it
- The Evidence Base for an Ideal Care Pathway for Frail Multimorbid Elderly: Combined Scoping and Systematic Intervention Review.Journal of medical Internet research · 2019Pooled it
- Role of comprehensive geriatric assessment in healthcare of older people in UK care homes: realist review.BMJ open · 2019Pooled it
- General health checks in adults for reducing morbidity and mortality from disease.The Cochrane database of systematic reviews · 2019Pooled it
- Effects of multi-domain interventions in (pre)frail elderly on frailty, functional, and cognitive status: a systematic review.Clinical interventions in aging · 2017Pooled it
- Time-limited home-care reablement services for maintaining and improving the functional independence of older adults.The Cochrane database of systematic reviews · 2016Pooled it
- Pooled it
- Systematic review of EASY-care needs assessment for community-dwelling older people.Age and ageing · 2015Pooled it
- Robot-assisted exercise improves gait and physical function in older adults: a usability study.BMC geriatrics · 2025Trial
- Study of a Quasi-Experimental Trial to Compare Two Models of Home Care for the Elderly in an Urban Primary Care Setting in Spain: Results of Intermediate Analysis.International journal of environmental research and public health · 2022Trial
216 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn old age, reduction in physical function leads to loss of independence, the need for hospital and long-term nursing-home care, and premature death. We did a systematic review to assess the effectiveness of community-based complex interventions in preservation of physical function and independence in elderly people.
methodsWe searched systematically for randomised controlled trials assessing community-based multifactorial interventions in elderly people (mean age at least 65 years) living at home with at least 6 months of follow-up. Outcomes studied were living at home, death, nursing-home and hospital admissions, falls, and physical function. We did a meta-analysis of the extracted data.
findingsWe identified 89 trials including 97 984 people. Interventions reduced the risk of not living at home (relative risk [RR] 0.95, 95% CI 0.93-0.97). Interventions reduced nursing-home admissions (0.87, 0.83-0.90), but not death (1.00, 0.97-1.02). Risk of hospital admissions (0.94, 0.91-0.97) and falls (0.90, 0.86-0.95) were reduced, and physical function (standardised mean difference -0.08, -0.11 to -0.06) was better in the intervention groups than in other groups. Benefit for any specific type or intensity of intervention was not noted. In populations with increased death rates, interventions were associated with reduced nursing-home admission. Benefit in trials was particularly evident in studies started before 1993.
interpretationComplex interventions can help elderly people to live safely and independently, and could be tailored to meet individuals' needs and preferences.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.