Evidence map›Paper›PMID 18312059›Full record

Trial reportThe Journal of clinical psychiatry2008

Prenatal depression in women hospitalized for obstetric risk.

Anna R Brandon, Madhukar H Trivedi, Linda S Hynan, Paula D Miltenberger, Dana Broussard Labat, Jamie B Rifkin, C Allen Stringer

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of clinical psychiatry, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02119936 (Feasibility of Heart Rate Variability Biofeedback as a Stress Reduction Tool for Hospitalized Pregnant Women at the University of North Carolina at Chapel Hill), which is not on this map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02119936 naterminatednot on this mapstarted 2014, after this paper: background citation

Feasibility of Heart Rate Variability Biofeedback as a Stress Reduction Tool for Hospitalized Pregnant Women at the University of North Carolina at Chapel Hill (UNC-CH)

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2014 to 2016Enrolled10ConditionsMaternal Stress, Maternal Anxiety, Maternal Health ServicesArmsHeart Rate Variability Biofeedback Tool
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 106 citations in OpenAlex.

  1. Pooled it
  2. Prenatal Attachment and Perinatal Depression: A Systematic Review.International journal of environmental research and public health · 2020
    Pooled it
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. There's no place like home: optimizing the antepartum inpatient experience.Maternal health, neonatology and perinatology · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Depression remains a neglected public health problem among pregnant women in Northwest Ethiopia.Archives of public health = Archives belges de sante publique · 2021
    Article
  17. Does having a high-risk pregnancy influence anxiety level during the COVID-19 pandemic?European journal of obstetrics, gynecology, and reproductive biology · 2020
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anna R BrandonUniversity of Texas Southwestern Medical Center at Dallas, Dallas, Tex 75390-9066, USA. anna.brandon@utsouthwestern.edu
Madhukar H Trivedi
Linda S Hynan
Paula D Miltenberger
Dana Broussard Labat
Jamie B Rifkin
C Allen Stringer
The University of Texas Southwestern Medical Center · USBaylor University Medical Center · US

Funding

NORTH AND CENTRAL TEXAS CTSA FOR PEDIATRIC RESEARCHUL1RR024982 · NCRR · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2007 to 2011
$27.9M
Southwestern Clinical Science Scholars Program (RMI)K12RR023251 · NCRR · UT SOUTHWESTERN MEDICAL CENTER · PI PACKER, MILTON · 2005 to 2007
$3.5M
NCRR NIH HHS K12 RR023251NCRR NIH HHS UL1 RR024982
6 · The paper itself

Abstract

objectiveLittle is known about depression during pregnancy in women with high maternal or fetal risk, as this population is often excluded from research samples. The aim of this study was to evaluate depressive symptoms and known risk factors for depression in a group of women hospitalized with severe obstetric risk.

methodIn the antenatal unit, 129 inpatients completed the Edinburgh Postnatal Depression Scale (EPDS), the Dyadic Adjustment Scale (DAS), and the Maternal Antenatal Attachment Scale (MAAS) from October 2005 through December 2006. A subset of women were administered the Mood Disorders module of the Structured Clinical Interview for DSM-IV Axis I Disorders based on a score of > or = 11 on the EPDS. Obstetric complications were classified according to the Hobel Risk Assessment for Prematurity.

resultsFifty-seven of the 129 women (44.2%) scored 11 or greater on the EPDS, and at least 25/129 (19.4%) met the DSM-IV criteria for major depressive disorder. Mothers reporting high attachment to the fetus on the MAAS reported lower severity of depressive symptoms (rho = -0.33, p < .0001); those reporting interpersonal relationship dissatisfaction on the DAS endorsed higher depressive severity (rho = -0.21, p = .02). Severity of obstetric risk was unrelated to depression, but one complication, incompetent cervix, was positively associated with level of depressive symptomatology.

conclusionFindings indicate a higher prevalence rate of major depressive disorder in women with severe obstetric risk than that reported in low-risk pregnancy samples, suggesting the need for routine depression screening to identify those who need treatment. Fewer depressive symptoms were reported by mothers reporting strong maternal fetal attachment and greater relationship satisfaction.

Indexed as

HospitalizationAdultFemaleHumansMajor Depressive DisorderPregnancyPregnancy ComplicationsPrenatal CareRisk Factors

Identifiers

PMID18312059
PMCPMC2680504
OpenAlexW2060317326

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.