ArticleJournal of bacteriology2008
Molecular analysis of three Aeromonas hydrophila AH-3 (serotype O34) lipopolysaccharide core biosynthesis gene clusters.
Article in Journal of bacteriology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 28 citations in OpenAlex.
- Architecture, Function, Regulation, and Evolution of α-Glucans Metabolic Enzymes in Prokaryotes.Chemical reviews · 2024Review
- Autoinducer-2 promotes adherence ofApplied and environmental microbiology · 2023Article
- Comparative genomic analysis ofFrontiers in microbiology · 2023Article
- Surface Glucan Structures inMarine drugs · 2021Review
- Structural Studies of the Lipopolysaccharide ofInternational journal of molecular sciences · 2021Article
- A Unique Sugar l-Perosamine (4-Amino-4,6-dideoxy-l-mannose) Is a Compound Building Two O-Chain Polysaccharides in the Lipopolysaccharide ofMarine drugs · 2019Article
- Comparative Genomics of the Aeromonadaceae Core Oligosaccharide Biosynthetic Regions.International journal of molecular sciences · 2017Article
- The Aeromonas salmonicida Lipopolysaccharide Core from Different Subspecies: The Unusual subsp. pectinolytica.Frontiers in microbiology · 2016Article
- The Animal Model Determines the Results ofFrontiers in microbiology · 2016Article
- Molecular and chemical analysis of the lipopolysaccharide from Aeromonas hydrophila strain AH-1 (Serotype O11).Marine drugs · 2015Article
- The Polymerization of Aeromonas hydrophila AH-3 O-Antigen LPS: Concerted Action of WecP and Wzy.PloS one · 2015Article
- Structural studies of the lipopolysaccharide from the fish pathogen Aeromonas veronii strain Bs19, serotype O16.Marine drugs · 2014Article
- Article
- Development of diagnostic and vaccine markers through cloning, expression, and regulation of putative virulence-protein-encoding genes of Aeromonas hydrophila.Journal of microbiology (Seoul, Korea) · 2013Review
- Article
- The main Aeromonas pathogenic factors.ISRN microbiology · 2012Article
- Aeromonas surface glucan attached through the O-antigen ligase represents a new way to obtain UDP-glucose.PloS one · 2012Article
- Article
- A bifunctional enzyme in a single gene catalyzes the incorporation of GlcN into the Aeromonas core lipopolysaccharide.The Journal of biological chemistry · 2009Article
- Genetics and proteomics of Aeromonas salmonicida lipopolysaccharide core biosynthesis.Journal of bacteriology · 2009Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
By the isolation of three different Aeromonas hydrophila strain AH-3 (serotype O34) mutants with an altered lipopolysaccharide (LPS) migration in gels, three genomic regions encompassing LPS core biosynthesis genes were identified and characterized. When possible, mutants were constructed using each gene from the three regions, containing seven, four, and two genes (regions 1 to 3, respectively). The mutant LPS core structures were elucidated by using mass spectrometry, methylation analysis, and comparison with the full core structure of an O-antigen-lacking AH-3 mutant previously established by us. Combining the gene sequence and complementation test data with the structural data and phenotypic characterization of the mutant LPSs enabled a presumptive assignment of all LPS core biosynthesis gene functions in A. hydrophila AH-3. The three regions and the genes contained are in complete agreement with the recently sequenced genome of A. hydrophila ATCC 7966. The functions of the A. hydrophila genes waaC in region 3 and waaF in region 2 were completely established, allowing the genome annotations of the two heptosyl transferase products not previously assigned. Having the functions of all genes involved with the LPS core biosynthesis and most corresponding single-gene mutants now allows experimental work on the role of the LPS core in the virulence of A. hydrophila.
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