ReviewClinical journal of the American Society of Nephrology : CJASN2008
Cancer screening in renal transplant recipients: what is the evidence?
Review in Clinical journal of the American Society of Nephrology : CJASN, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 116 citations in OpenAlex.
- De novo colorectal cancer after kidney transplantation: a systematic review and meta-analysis.British journal of cancer · 2025Pooled it
- Pooled it
- Anal HPV in Kidney Transplant Recipients: A Closer Look at Pathogenesis and Clinical Management.Pathogens (Basel, Switzerland) · 2026Review
- Non-Melanoma Skin Cancer in Transplant Recipients: A Single-Centre Retrospective Cohort Study on the Role of Transplant Type, Immunosuppressive Exposure, and Tumor Subtypes.Clinical transplantation · 2026Article
- Clinical management of cancer after kidney transplantation.Frontiers in immunology · 2026Review
- Early-Onset Bilateral Clear Cell Renal Cell Carcinoma in a Pediatric Renal Transplant Recipient: A Rare Case Report.Case reports in urology · 2026Article
- Epidemiological Overview of Colorectal Cancer in Kidney Transplant Recipients: A Systematic Review.Cancers · 2025Review
- Mammographic Calcifications in Lung Transplant Recipients: Prevalence and Evolution.Biomedicines · 2025Article
- Increased cancer risk in kidney transplant patients in Scotland: a national registry linkage study.British journal of cancer · 2025Article
- Article
- Risk factors for cancer and the importance of screening in adult recipients of living-donor kidney transplant.Frontiers in immunology · 2025Article
- Incidence, Risk Factors, and Outcomes of De Novo Malignancy following Kidney Transplantation.Journal of clinical medicine · 2024Article
- A Global Survey of Self-Reported Cancer Screening Practices by Health Professionals for Kidney Transplant Candidates and Recipients.Transplant international : official journal of the European Society for Organ Transplantation · 2024Article
- Incidence ofTransplant international : official journal of the European Society for Organ Transplantation · 2024Article
- Screening for renal cell carcinoma in renal transplant recipients: a single-centre retrospective study.BMJ open · 2023Article
- Human papillomavirus anogenital screening in solid organ transplant recipients: a narrative review.Archives of gynecology and obstetrics · 2023Review
- Review
- Incidence and Outcomes of Early Cancers After Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2022Article
- Emerging Concepts in Managing Malignancy in Kidney Transplant Patients.Seminars in nephrology · 2022Review
- Colorectal Cancer after Kidney Transplantation: A Screening Colonoscopy Case-Control Study.Biomedicines · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increased cancer risk is well established in the renal transplant population. Little, however, is known about the benefits and harms of cancer screening, treatment effectiveness, and the overall cancer prognosis in renal transplant recipients. In this study, we critically appraised guidelines for cancer screening in the renal transplant and general populations using standard criteria for an evidence-based screening program. Guidelines were included when they were applied to adult participants, had objectives specific to cancer screening, and were written in English. Recommendations for breast and colorectal cancer screening in the general population were supported by evidence of cancer-specific mortality benefits from randomized, controlled trials of cancer screening. Convincing evidence from observational studies had demonstrated population cervical cancer screening was effective, also, test performance of mammography, faecal occult blood testing, and Pap smear were accurate. Population breast, colorectal, and cervical cancer screening also appeared to be good value for money in the general population. On the contrary, recommendations for cancer screening in renal transplant recipients were entirely extrapolated from data in the general population. Studies in the general population have led to the development of cancer screening guidelines in transplant recipients. Because of increased cancer risk, differences in diagnostic test performance, competing risks for deaths from causes such as cardiovascular disease and reduced overall life expectancies, validity of their recommendations are uncertain. Future studies are needed to address these issues to provide the necessary evidence for informed decision-making.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.