ArticleBMC plant biology2008
Co-expression and promoter content analyses assign a role in biotic and abiotic stress responses to plant natriuretic peptides.
Article in BMC plant biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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38 citing papers in PubMed, 76 citations in OpenAlex.
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- Citrus Canker Pathogen, Its Mechanism of Infection, Eradication, and Impacts.Plants (Basel, Switzerland) · 2022Review
- Application of the NanoString nCounter System as an Alternative Method to Investigate Molecular Mechanisms Involved in Host Plant Responses toInternational journal of molecular sciences · 2022Article
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- Differential root and shoot magnetoresponses in Arabidopsis thaliana.Scientific reports · 2021Article
- Multi-responses of O-methyltransferase genes to salt stress and fiber development of Gossypium species.BMC plant biology · 2021Article
- Arabidopsis Plant Natriuretic Peptide Is a Novel Interactor of Rubisco Activase.Life (Basel, Switzerland) · 2020Article
- A natriuretic peptide from Arabidopsis thaliana (AtPNP-A) can modulate catalase 2 activity.Scientific reports · 2020Article
- PLANT NATRIURETIC PEPTIDE A and Its Putative Receptor PNP-R2 Antagonize Salicylic Acid-Mediated Signaling and Cell Death.The Plant cell · 2020Article
- Response ofFrontiers in plant science · 2020Article
- Functional characterization of genes mediating cell wall metabolism and responses to plant cell wall integrity impairment.BMC plant biology · 2019Article
- Bacterial and plant natriuretic peptides improve plant defence responses against pathogens.Molecular plant pathology · 2018Article
- Transcriptomic analysis of Arabidopsis thaliana plants treated with the Ky-9 and Ky-72 histone deacetylase inhibitors.Plant signaling & behavior · 2018Article
- The arabidopsis cyclic nucleotide interactome.Cell communication and signaling : CCS · 2016Article
- Transcriptome and hormone profiling reveals Eucalyptus grandis defence responses against Chrysoporthe austroafricana.BMC genomics · 2015Article
- Quantitative phosphoproteomics of the ataxia telangiectasia-mutated (ATM) and ataxia telangiectasia-mutated and rad3-related (ATR) dependent DNA damage response in Arabidopsis thaliana.Molecular & cellular proteomics : MCP · 2015Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPlant natriuretic peptides (PNPs) are a class of systemically mobile molecules distantly related to expansins. While several physiological responses to PNPs have been reported, their biological role has remained elusive. Here we use a combination of expression correlation analysis, meta-analysis of gene expression profiles in response to specific stimuli and in selected mutants, and promoter content analysis to infer the biological role of the Arabidopsis thaliana PNP, AtPNP-A.
resultsA gene ontology analysis of AtPNP-A and the 25 most expression correlated genes revealed a significant over representation of genes annotated as part of the systemic acquired resistance (SAR) pathway. Transcription of these genes is strongly induced in response to salicylic acid (SA) and its functional synthetic analogue benzothiadiazole S-methylester (BTH), a number of biotic and abiotic stresses including many SA-mediated SAR-inducing conditions, as well as in the constitutive SAR expressing mutants cpr5 and mpk4 which have elevated SA levels. Furthermore, the expression of AtPNP-A was determined to be significantly correlated with the SAR annotated transcription factor, WRKY 70, and the promoters of AtPNP-A and the correlated genes contain an enrichment in the core WRKY binding W-box cis-elements. In constitutively expressing WRKY 70 lines the expression of AtPNP-A and the correlated genes, including the SAR marker genes, PR-2 and PR-5, were determined to be strongly induced.
conclusionThe co-expression analyses, both in wild type and mutants, provides compelling evidence that suggests AtPNP-A may function as a component of plant defence responses and SAR in particular. The presented evidence also suggests that the expression of AtPNP-A is controlled by WRKY transcription factors and WRKY 70 in particular. AtPNP-A shares many characteristics with PR proteins in that its transcription is strongly induced in response to pathogen challenges, it contains an N-terminal signalling peptide and is secreted into the extracellular space and along with PR-1, PR-2 and PR-5 proteins it has been isolated from the Arabidopsis apoplast. Based on these findings we suggest that AtPNP-A could be classified as a newly identified PR protein.
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