Evidence map›Paper›PMID 18306040›Full record

ReviewDigestive diseases and sciences2008

Risk factors for gastrointestinal complications in aspirin users: review of clinical and experimental data.

Felix W Leung

Abstract readReview
PubMed Publisher
In one paragraph

Review in Digestive diseases and sciences, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Felix W LeungDivision of Gastroenterology, Research and Medical Services, Sepulveda Ambulatory Care Center, VA Greater Los Angeles Healthcare System, 111G, 16111 Plummer Street, Sepulveda, CA 91343, USA. felix.leung@va.gov
VA Sepulveda Ambulatory Care Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper reviews recent clinical evidence that suggests that aspirin prophylaxis against cardiac and cerebral vascular ischemia is associated with significant gastrointestinal complications. The clinical and experimental evidence to confirm the role of risk factors of concomitant use of nonsteroidal anti-inflammatory drugs (NSAID), tobacco cigarette smoking, and alcohol consumption are discussed. The limitations of long-term acid suppression treatment for the prevention of these complications are considered. Future experimental studies to guide the clinical approach to develop novel and potentially cost-effective management strategies are discussed.

Indexed as

Alcohol DrinkingAnti-Inflammatory Agents, Non-SteroidalAspirinHumansRisk FactorsSmokingStomach UlcerVascular DiseasesAnti-Inflammatory Agents, Non-SteroidalAspirin

Identifiers

PMID18306040
OpenAlexW2000342382

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.