ArticlePlant physiology2008
Arabidopsis PPR40 connects abiotic stress responses to mitochondrial electron transport.
Article in Plant physiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.
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Who cites it
89 citing papers in PubMed, 202 citations in OpenAlex.
- Crops exposed to extreme conditions: perspectives of gene editing to improve stress tolerance.Plant cell reports · 2026Review
- Novel Molecular Markers and Immune-Related Candidate Genes for Blackleg Resistance in Rapeseed: A Genome-Wide Analysis.International journal of molecular sciences · 2026Article
- Natural Variation of a PPR Coding Gene SST1 Confers Salt Tolerance During Soybean Domestication.Plant biotechnology journal · 2026Article
- Physiological and molecular response of soybean to combined drought and heat stresses during flowering.BMC plant biology · 2026Article
- miRNA-Mediated Regulation ofInternational journal of molecular sciences · 2025Article
- Bioinformatics Analysis Reveals PPR Genes Modulation by Ahyp-miR0005 Under Abiotic Stress Across Diverse Plant Species.Plants (Basel, Switzerland) · 2025Article
- TaPPR13, a Pentatricopeptide Repeat Protein Gene Activated by TaBZR2, Confers Drought Stress Tolerance by Enhancing the Antioxidant Defense System and Promoting Retrograde Signaling in Wheat (Triticum aestivum).Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- CmPPR4 gene controls drought resilience in melon ecotypes.Plant biotechnology journal · 2025Article
- The Regulatory Roles of RNA-Binding Proteins in Plant Salt Stress Response.Plants (Basel, Switzerland) · 2025Review
- Pentatricopeptide repeat proteins in plants: Cellular functions, action mechanisms, and potential applications.Plant communications · 2025Review
- Long-Term Salinity-Responsive Transcriptome in Advanced Breeding Lines of Tomato.Plants (Basel, Switzerland) · 2025Article
- SeqSNP-Based Targeted GBS Provides Insight into the Genetic Relationships among Global Collections ofGenes · 2024Article
- Article
- Landscape genomics reveals genetic signals of environmental adaptation of African wild eggplants.Ecology and evolution · 2024Article
- Genomic insights into local adaptation and vulnerability of Quercus longinux to climate change.BMC plant biology · 2024Article
- Mutation in Arabidopsis mitochondrial Pentatricopeptide repeat 40 gene affects tolerance to water deficit.Planta · 2024Article
- Bio Prospecting of Endophytes and PGPRs in Artemisinin Production for the Socio-economic Advancement.Current microbiology · 2023Review
- A Genome-Wide Analysis of the Pentatricopeptide Repeat Protein Gene Family in Two Kiwifruit Species with an Emphasis on the Role of RNA Editing in Pathogen Stress.International journal of molecular sciences · 2023Article
- Multiomics Reveals the Regulatory Mechanisms of Arabidopsis Tissues under Heat Stress.International journal of molecular sciences · 2023Article
- Comparative transcriptome analysis of Zea mays upon mechanical wounding.Molecular biology reports · 2023Article
29 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oxidative respiration produces adenosine triphosphate through the mitochondrial electron transport system controlling the energy supply of plant cells. Here we describe a mitochondrial pentatricopeptide repeat (PPR) domain protein, PPR40, which provides a signaling link between mitochondrial electron transport and regulation of stress and hormonal responses in Arabidopsis (Arabidopsis thaliana). Insertion mutations inactivating PPR40 result in semidwarf growth habit and enhanced sensitivity to salt, abscisic acid, and oxidative stress. Genetic complementation by overexpression of PPR40 complementary DNA restores the ppr40 mutant phenotype to wild type. The PPR40 protein is localized in the mitochondria and found in association with Complex III of the electron transport system. In the ppr40-1 mutant the electron transport through Complex III is strongly reduced, whereas Complex IV is functional, indicating that PPR40 is important for the ubiqinol-cytochrome c oxidoreductase activity of Complex III. Enhanced stress sensitivity of the ppr40-1 mutant is accompanied by accumulation of reactive oxygen species, enhanced lipid peroxidation, higher superoxide dismutase activity, and altered activation of several stress-responsive genes including the alternative oxidase AOX1d. These results suggest a close link between regulation of oxidative respiration and environmental adaptation in Arabidopsis.
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