ArticleAmerican journal of human genetics2008
Genome-wide scan and fine-mapping linkage study of androgenetic alopecia reveals a locus on chromosome 3q26.
Article in American journal of human genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 78 citations in OpenAlex.
- "Cold" X5 Hairlaser™ used to treat male androgenic alopecia and hair growth: an uncontrolled pilot study.BMC research notes · 2014Trial
- The Genetic Landscape of Androgenetic Alopecia: Current Knowledge and Future Perspectives.Biology · 2026Review
- Use of genetics in the prediction of success in male pattern hair loss therapy and mechanistic studies.Frontiers in pharmacology · 2026Review
- Relationship of Hypothyroidism with Alopecia Areata and Androgenetic Alopecia: Insights from a Two-Sample Mendelian Randomization Study.Clinical, cosmetic and investigational dermatology · 2024Article
- Mapping of cis-acting expression quantitative trait loci in human scalp hair follicles.BMC dermatology · 2020Article
- Early-onset androgenetic alopecia in China: a descriptive study of a large outpatient cohort.The Journal of international medical research · 2020Article
- Androgenetic Alopecia: Relationship to Anthropometric Indices, Blood Pressure and Life-Style Habits.Clinical, cosmetic and investigational dermatology · 2020Article
- Genetic variations associated with response to dutasteride in the treatment of male subjects with androgenetic alopecia.PloS one · 2019Article
- Female pattern hair loss: A clinical, pathophysiologic, and therapeutic review.International journal of women's dermatology · 2018Review
- Relationship between male pattern baldness and the risk of aggressive prostate cancer: an analysis of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2015Article
- Assessment of the usefulness of dihydrotestosterone in the diagnostics of patients with androgenetic alopecia.Postepy dermatologii i alergologii · 2014Article
- Minoxidil may suppress androgen receptor-related functions.Oncotarget · 2014Article
- Article
- Alterations in sensitivity to estrogen, dihydrotestosterone, and xenogens in B-lymphocytes from children with autism spectrum disorder and their unaffected twins/siblings.Journal of toxicology · 2013Article
- The role of androgen and androgen receptor in skin-related disorders.Archives of dermatological research · 2012Review
- Characteristics of androgenetic alopecia in asian.Annals of dermatology · 2012Article
- Article
- Recent positive selection of a human androgen receptor/ectodysplasin A2 receptor haplotype and its relationship to male pattern baldness.Human genetics · 2009Article
- Study of the International Epidemiology of Androgenetic Alopecia in Young Caucasian Men Using Photographs From the Internet.Indian journal of dermatologyArticle
Corrections and comments
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Authors and funding
16 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Androgenetic alopecia (AGA, male pattern baldness) is the most common form of hair loss. The origin of AGA is genetic, with the X chromosome located androgen receptor gene (AR) being the only risk gene identified to date. We present the results of a genome-wide linkage study of 95 families and linkage fine mapping of the 3q21-q29, 11q14-q25, 18p11-q23, and 19p13-q13 regions in an extended sample of 125 families of German descent. The locus with strongest evidence for linkage was mapped to 3q26 with a nonparametric linkage (NPL) score of 3.97 (empirical p value = 0.00055). This is the first step toward the identification of new susceptibility genes in AGA, a process which will provide important insights into the molecular and cellular basis of scalp hair loss.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.