ArticleNeuron2008
Odor representations in the rat olfactory bulb change smoothly with morphing stimuli.
Article in Neuron, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Mouse olfactory system acts as anemo-detector and anemo-discriminator.Science advances · 2025Article
- Firing Patterns of Mitral Cells and Their Transformation in the Main Olfactory Bulb.Brain sciences · 2024Article
- Decomposition of an odorant in olfactory perception and neural representation.Nature human behaviour · 2024Article
- Changes in spontaneous and odorant-induced single-unit activity of mitral/tufted neurons of the rat olfactory bulb during xylazine-tiletamine-zolazepam anesthesia.IBRO neuroscience reports · 2022Article
- Structural spine plasticity: Learning and forgetting of odor-specific subnetworks in the olfactory bulb.PLoS computational biology · 2022Article
- Aversive outcomes impact human olfactory discrimination learning and generalization.Behavioral neuroscience · 2021Article
- Stimulus Driven Functional Transformations in the Early Olfactory System.Frontiers in cellular neuroscience · 2021Article
- Competitive binding predicts nonlinear responses of olfactory receptors to complex mixtures.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Nostril-specific and structure-based olfactory learning of chiral discrimination in human adults.eLife · 2019Article
- Inhalation Frequency Controls Reformatting of Mitral/Tufted Cell Odor Representations in the Olfactory Bulb.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Control of Mitral/Tufted Cell Output by Selective Inhibition among Olfactory Bulb Glomeruli.Neuron · 2016Article
- ϒ spike-field coherence in a population of olfactory bulb neurons differentiates between odors irrespective of associated outcome.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Olfactory bulb coding of odors, mixtures and sniffs is a linear sum of odor time profiles.Nature neuroscience · 2015Article
- Bulbar microcircuit model predicts connectivity and roles of interneurons in odor coding.PloS one · 2015Article
- Extracting Social Information from Chemosensory Cues: Consideration of Several Scenarios and Their Functional Implications.Frontiers in neuroscience · 2015Article
- Broadly tuned and respiration-independent inhibition in the olfactory bulb of awake mice.Nature neuroscience · 2014Article
- Understanding odor information segregation in the olfactory bulb by means of mitral and tufted cells.PloS one · 2014Article
- Encoding of mixtures in a simple olfactory system.Neuron · 2013Article
- Synchronous firing of antennal-lobe projection neurons encodes the behaviorally effective ratio of sex-pheromone components in male Manduca sexta.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2013Article
- Neural dynamics in response to binary taste mixtures.Journal of neurophysiology · 2013Article
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3 authors.
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Abstract
Many species of mammals are very good at categorizing odors. One model for how this is achieved involves the formation of "attractor" states in the olfactory processing pathway, which converge to stable representations for the odor. We analyzed the responses of rat olfactory bulb mitral/tufted (M/T) cells using stimuli "morphing" from one odor to another through intermediate mixtures. We then developed a phenomenological model for the representation of odors and mixtures by M/T cells and show that >80% of odorant responses to different concentrations and mixtures can be expressed in terms of smoothly summing responses to air and the two pure odorants. Furthermore, the model successfully predicts M/T cell responses to odor mixtures when respiration dependence is eliminated. Thus, odor mixtures are represented in the bulb through summation of components, rather than distinct attractor states. We suggest that our olfactory coding model captures many aspects of single and mixed odor representation in M/T cells.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.