ArticleMammalian genome : official journal of the International Mammalian Genome Society2008
An imputed genotype resource for the laboratory mouse.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
58 citing papers in PubMed, 1 synthesis or guideline pooled it.
- GenomeMUSter mouse genetic variation service enables multitrait, multipopulation data integration and analysis.Genome research · 2024Pooled it
- Variable outcomes of human heart attack recapitulated in genetically diverse mice.NPJ Regenerative medicine · 2019Article
- Exome sequencing analysis of murine medulloblastoma models identifies WDR11 as a potential tumor suppressor in Group 3 tumors.Oncotarget · 2017Article
- Sex chromosomes drive gene expression and regulatory dimorphisms in mouse embryonic stem cells.Biology of sex differences · 2017Article
- Initial locomotor sensitivity to cocaine varies widely among inbred mouse strains.Genes, brain, and behavior · 2015Article
- Fine-mapping QTLs in advanced intercross lines and other outbred populations.Mammalian genome : official journal of the International Mammalian Genome Society · 2014Review
- Seeking genetic signature of radiosensitivity--a novel method for data analysis in case of small sample sizes.Theoretical biology & medical modelling · 2014Article
- Repetitive behavior profile and supersensitivity to amphetamine in the C58/J mouse model of autism.Behavioural brain research · 2014Article
- Bugs in the system.Immunological reviews · 2013Review
- Deconstructing Mus gemischus: advances in understanding ancestry, structure, and variation in the genome of the laboratory mouse.Mammalian genome : official journal of the International Mammalian Genome Society · 2013Review
- Differences in health status affect susceptibility and mapping of genetic loci for atherosclerosis (fatty streak) in inbred mice.Arteriosclerosis, thrombosis, and vascular biology · 2012Article
- Genetic coregulation of age of female sexual maturation and lifespan through circulating IGF1 among inbred mouse strains.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains.Psychopharmacology · 2012Article
- Article
- Integration of QTL and bioinformatic tools to identify candidate genes for triglycerides in mice.Journal of lipid research · 2011Article
- Identification of fat4 and tsc22d1 as novel candidate genes for spontaneous pulmonary adenomas.Cancer research · 2011Article
- Genetic analysis of complex traits in the emerging Collaborative Cross.Genome research · 2011Article
- The mouse QTL map helps interpret human genome-wide association studies for HDL cholesterol.Journal of lipid research · 2011Article
- Subspecific origin and haplotype diversity in the laboratory mouse.Nature genetics · 2011Article
- Genetic analysis of mouse strains with variable serum sodium concentrations identifies the Nalcn sodium channel as a novel player in osmoregulation.Physiological genomics · 2011Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
We have created a high-density SNP resource encompassing 7.87 million polymorphic loci across 49 inbred mouse strains of the laboratory mouse by combining data available from public databases and training a hidden Markov model to impute missing genotypes in the combined data. The strong linkage disequilibrium found in dense sets of SNP markers in the laboratory mouse provides the basis for accurate imputation. Using genotypes from eight independent SNP resources, we empirically validated the quality of the imputed genotypes and demonstrated that they are highly reliable for most inbred strains. The imputed SNP resource will be useful for studies of natural variation and complex traits. It will facilitate association study designs by providing high-density SNP genotypes for large numbers of mouse strains. We anticipate that this resource will continue to evolve as new genotype data become available for laboratory mouse strains. The data are available for bulk download or query at http://cgd.jax.org /.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.