ArticleWorld journal of gastroenterology2008
P wave dispersion is prolonged in patients with Wilson's disease.
Article in World journal of gastroenterology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-analysis of p-wave dispersion values in healthy individuals: the influence of clinical characteristics.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2012Pooled it
- Cardiac involvement in Wilson disease: pathophysiology, clinical spectrum, and multimodality imaging assessment.Frontiers in cardiovascular medicine · 2026Review
- Cardiac assessment in Wilson's disease patients based on electrocardiography and echocardiography examination.Archives of medical science : AMS · 2019Article
- Cardiac and autonomic function in patients with Wilson's disease.Orphanet journal of rare diseases · 2019Article
- Noninvasive evaluation of reverse atrial remodeling after catheter ablation of atrial fibrillation by P wave dispersion.Heart and vessels · 2017Article
- Atrial Fibrillation and Beta Thalassemia Major: The Predictive Role of the 12-lead Electrocardiogram Analysis.Indian pacing and electrophysiology journal · 2014Article
- Modifying factors and phenotypic diversity in Wilson's disease.Annals of the New York Academy of Sciences · 2014Review
- Early electrocardiographic evaluation of atrial fibrillation risk in beta-thalassemia major patients.International journal of hematology · 2011Article
- Strain and strain rate echocardiography in children with Wilson's disease.Cardiovascular journal of AfricaArticle
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the P wave dispersion as a non-invasive marker of intra-atrial conduction disturbances in patients with Wilson's disease.
methodsWe compared Wilsonos disease patients (n = 18) with age matched healthy subjects (n = 15) as controls. The diagnosis was based on clinical symptoms, laboratory tests (ceruloplasmin, urinary and hepatic copper concentrations). P wave dispersion, a measurement of the heterogeneity of atrial depolarization, was measured as the difference between the duration of the longest and the shortest P-waves in 12 lead electrocardiography.
resultsAll the patients were asymptomatic on cardiological examination and have sinusal rhythm in electrocardiography. Left ventricular and left atrial diameters, left ventricular ejection fraction and left ventricular mass index were similar in both groups. The Wilson's disease patients had a significantly higher P wave dispersion compared with the controls (44.7 +/- 5.8 vs 25.7 +/- 2.5, P < 0.01).
conclusionThere was an increase in P wave dispersion in cardiologically asymptomatic Wilson's disease patients which probably represents an early stage of cardiac involvement.
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