Evidence map›Paper›PMID 18300000›Full record

ReviewJournal of molecular neuroscience : MN2008

Features and functions of oligodendrocytes and myelin proteins of lower vertebrate species.

Gunnar Jeserich, Katrin Klempahn, Melanie Pfeiffer

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of molecular neuroscience : MN, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. The Current Challenges for Drug Discovery in CNS Remyelination.International journal of molecular sciences · 2021
    Review
  6. Review
  7. Article
  8. Article
  9. No Nogo66- and NgR-mediated inhibition of regenerating axons in the zebrafish optic nerve.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2009
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Gunnar JeserichDept. Neurobiology, University of Osnabrück, Barbarastr. 11, 49069 Osnabrück, Germany. jeserich@biologie.uni-osnabruck.de
Katrin Klempahn
Melanie Pfeiffer
Osnabrück University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The myelin-forming cells in the central nervous system (CNS) of lower vertebrate species, in particular those of fish, profoundly differ from their mammalian counterparts in their biochemical phenotype in that they express Po-like glycoproteins as major myelin protein constituents instead of proteolipid protein, while in their overall cellular structure and their cell lineage relationships, they closely resemble mammalian oligodendrocytes. While molecular biology in the past has allowed to appropriately classify the major myelin proteins synthesized by fish oligodendrocytes, heterologous expression studies are expected to give a deeper insight into the particular features and the conserved functions of these proteins required for myelin formation and maintenance in fish. It is hoped that this approach will also help to improve our understanding of the molecular processes underlying the unique capacity of fish oligodendrocytes for remyelination after injury in the CNS. This survey may stimulate neuroscientists to engage into this exciting field.

Indexed as

2',3'-Cyclic-Nucleotide PhosphodiesterasesAnimalsBiological TransportFishesMyelin ProteinsOligodendrogliaRecombinant Fusion Proteins2',3'-Cyclic-Nucleotide PhosphodiesterasesMyelin ProteinsRecombinant Fusion Proteins

Identifiers

PMID18300000
OpenAlexW2066918973

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.