ArticleThe Journal of biological chemistry2008
Six peptide wound signals derived from a single precursor protein in Ipomoea batatas leaves activate the expression of the defense gene sporamin.
Article in The Journal of biological chemistry, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Metabolomic and volatile profiling reveals defence-related effects of IbPep1 in sweet potato cell culture.BMC plant biology · 2026Article
- Plant Defense Responses to Insect Herbivores Through Molecular Signaling, Secondary Metabolites, and Associated Epigenetic Regulation.Plant-environment interactions (Hoboken, N.J.) · 2025Review
- Peptide hormones in plants.Molecular horticulture · 2025Review
- Pull the fuzes: Processing protein precursors to generate apoplastic danger signals for triggering plant immunity.Plant communications · 2024Review
- Influences ofCurrent protein & peptide science · 2024Article
- Automated Real-Time Monitoring of Extracellular pH to Assess Early Plant Defense Signaling.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Plant Responses to Herbivory, Wounding, and Infection.International journal of molecular sciences · 2022Review
- Molecular tug-of-war: Plant immune recognition of herbivory.The Plant cell · 2022Review
- Piriformospora indica colonization increases the growth, development, and herbivory resistance of sweet potato (Ipomoea batatas L.).Plant cell reports · 2021Article
- Phytocytokines function as immunological modulators of plant immunity.Stress biology · 2021Review
- Identification of endogenous small peptides involved in rice immunity through transcriptomics- and proteomics-based screening.Plant biotechnology journal · 2020Article
- Elicitor and Receptor Molecules: Orchestrators of Plant Defense and Immunity.International journal of molecular sciences · 2020Review
- Breaking Bad News: Dynamic Molecular Mechanisms of Wound Response in Plants.Frontiers in plant science · 2020Review
- Volatile DMNT systemically induces jasmonate-independent direct anti-herbivore defense in leaves of sweet potato (Ipomoea batatas) plants.Scientific reports · 2019Article
- Article
- Improvement for agronomically important traits by gene engineering in sweetpotato.Breeding science · 2017Review
- Extracellular Alkalinization as a Defense Response in Potato Cells.Frontiers in plant science · 2017Article
- DAMPs, MAMPs, and NAMPs in plant innate immunity.BMC plant biology · 2016Review
- Novel MtCEP1 peptides produced in vivo differentially regulate root development in Medicago truncatula.Journal of experimental botany · 2015Article
- The Plant Peptidome: An Expanding Repertoire of Structural Features and Biological Functions.The Plant cell · 2015Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
A mixture of three homologous bioactive hydroxyproline-rich glycopeptides (HypSys peptides) of 18 amino acids in length, differing only at two residues, was isolated from leaves of Ipomoea batatas, the common sweet potato. One of the peptides represented over 95% of the isolated isopeptides, which, at 2.5 nm concentration, induced the expression of sporamin, a major defense protein of I. batatas. The sequence of the major isoform was used to synthesize a primer that identified a cDNA encoding a precursor protein. The protein contained six proline-rich regions whose sequences suggested that they might be HypSys defense signals. One of the encoded peptides, called IbHypSys IV, was identical to one of two minor components of the isolated isopeptides, but neither the major isopeptide nor the other minor isoform was found within the precursor. The six peptides encoded by the precursor gene were synthesized but with hydroxyproline residues at positions found in the native isoforms and lacking carbohydrate moieties. All of the peptides were biologically active when supplied to leaves of sweet potato plants. The gene is the first ortholog of the preproHypSys gene family to be found outside of the Solanaceae family, and its encoded peptide precursor is the first example in plants of a precursor protein with six potential peptide defense signals, a scenario only found previously in animals. The data indicate that multiple copies of the HypSys peptides in a single precursor may have an important role in amplifying wound signaling in leaves in response to herbivore attacks.
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Registered trials
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