Evidence map›Paper›PMID 18298549›Full record

ReviewImmunology2008

Genomics and the immune system.

Matthew E Pipkin, Silvia Monticelli

Open access · bronzeAbstract readReview
In one paragraph

Review in Immunology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. MicroRNA expression profiles predictive of human renal allograft status.Proceedings of the National Academy of Sciences of the United States of America · 2009
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Matthew E PipkinImmune Disease Institute and Harvard Medical School, Boston, MA, USA.
Silvia Monticelli
Harvard University · US

Funding

Mechanics of LCR action on perforin to establish cytotoxicity in NK cells and CTLF32CA126247 · NCI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI PIPKIN, MATTHEW EUGENE · 2007 to 2010
$155k
NCI NIH HHS F32 CA126247
6 · The paper itself

Abstract

While the hereditary information encoded in the Watson-Crick base pairing of genomes is largely static within a given individual, access to this information is controlled by dynamic mechanisms. The human genome is pervasively transcribed, but the roles played by the majority of the non-protein-coding genome sequences are still largely unknown. In this review we focus on insights to gene transcriptional regulation by placing special emphasis on genome-wide approaches, and on how non-coding RNAs, which derive from global transcription of the genome, in turn control gene expression. We review recent progress in the field with highlights on the immune system.

Indexed as

AnimalsDNA-Binding ProteinsEpigenesis, GeneticGene Expression RegulationGenomicsHumansImmune SystemNucleosomesRNA, UntranslatedTranscription, GeneticDNA-Binding ProteinsNucleosomesRNA, Untranslated

Identifiers

PMID18298549
PMCPMC2434389
OpenAlexW2152692547

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.