Evidence map›Paper›PMID 18298044›Full record

ArticleFolia microbiologica2007

Apoptosis and aging in mitochondrial morphology mutants of S. cerevisiae.

V Palermo, C Falcone, C Mazzoni

Abstract read
PubMed Publisher
In one paragraph

Article in Folia microbiologica, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Yeast Lsm Pro-Apoptotic Mutants Show Defects in Autophagy.International journal of molecular sciences · 2023
    Article
  3. Article
  4. Article
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  7. Article
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  9. Article
  10. Review
  11. Article
  12. Increased levels of RNA oxidation enhance the reversion frequency in aging pro-apoptotic yeast mutants.Apoptosis : an international journal on programmed cell death · 2017
    Article
  13. External and internal triggers of cell death in yeast.Cellular and molecular life sciences : CMLS · 2016
    Review
  14. Article
  15. Review
  16. Mitochondrial stress signaling promotes cellular adaptations.International journal of cell biology · 2014
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

V PalermoDepartment of Cell and Developmental Biology, Pasteur Institute-Cenci Bolognetti Foundation, University of Rome La Sapienza, 5 00185 Rome, Italy.
C Falcone
C Mazzoni
Istituto Pasteur · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell viability during chronological aging and after apoptotic stimuli in some yeast mutants with altered mitochondrial morphology was followed; a function for the corresponding genes in the apoptotic process was assessed. MDM30 and DNM1, the genes encoding an F-box protein and the dynamin-related GTPase, respectively, are involved in triggering aging and apoptosis. In contrast, YME1, encoding a subunit of the mitochondrial inner membrane i-AAA proteinase complex, has a protective role in these processes. FIS1, the mitochondrial fission gene, might play a protective role after an apoptotic insult while it seems to promote cell death in aging cells.

Indexed as

MutationAdenosine TriphosphatasesApoptosisATP-Dependent ProteasesF-Box ProteinsF FactorGTP PhosphohydrolasesMitochondriaMitochondrial ProteinsOxidative StressSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsAdenosine TriphosphatasesATP-Dependent ProteasesDNM1 protein, S cerevisiaeF-Box ProteinsFIS1 protein, S cerevisiaeGTP PhosphohydrolasesMdm30 protein, S cerevisiaeMitochondrial ProteinsSaccharomyces cerevisiae ProteinsYME1 protein, S cerevisiae

Identifiers

PMID18298044
OpenAlexW2142893950

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.