Evidence map›Paper›PMID 18297169›Full record

ReviewBulletin of the World Health Organization2008

Vaccination greatly reduces disease, disability, death and inequity worldwide.

F E Andre, R Booy, H L Bock, J Clemens, S K Datta, T J John, B W Lee, S Lolekha, H Peltola, T A Ruff and 2 more

2 registry-linked trialsOpen access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Bulletin of the World Health Organization, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 530 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
530citing papers in PubMed, 8 pooled it
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03144518 nacompletednot on this mapstarted 2017, after this paper: background citation

A Feasibility Trial of a Brief Positive Affect Intervention to Improve the Effectiveness of Influenza Vaccine Response in Older Adults.

TypeinterventionalSponsorUniversity of NottinghamRan2017 to 2018Enrolled106ConditionsVaccination, InfectionArmsPositive Affect Intervention, Neutral Control Intervention, Northern Hemisphere Influenza Vaccine 2017/18 (Delivered as part of Standard Care)
NCT03956329 nacompletednot on this mapstarted 2019, after this paper: background citation

Enhancing Influenza Vaccination by Optimising Mood in Older Adults: a Randomised Controlled Clinical Trial

TypeinterventionalSponsorUniversity of NottinghamRan2019 to 2020Enrolled654ConditionsVaccination, InfectionArmsStandardised Digital Intervention, Individualised Digital Intervention
3 · Its place in the literature

Who cites it

530 citing papers in PubMed, 8 syntheses or guidelines pooled it, 1,244 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Trial
  10. Three-year Efficacy and Safety of Takeda's Dengue Vaccine Candidate (TAK-003).Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Trial
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review

470 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 8 countries.

F E Andrefeandre@yahoo.com
R Booy
H L Bock
J Clemens
S K Datta
T J John
B W Lee
S Lolekha
H Peltola
T A Ruff
M Santosham
H J Schmitt
GlaxoSmithKline (Belgium) · BEHelsinki University Hospital · FIInternational Vaccine Institute · KRJohannes Gutenberg University Mainz · DENational Centre for Immunisation Research & Surveillance · AUNational University of Singapore · SGRamathibodi Hospital · THUniversity of Melbourne · AUYahoo (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In low-income countries, infectious diseases still account for a large proportion of deaths, highlighting health inequities largely caused by economic differences. Vaccination can cut health-care costs and reduce these inequities. Disease control, elimination or eradication can save billions of US dollars for communities and countries. Vaccines have lowered the incidence of hepatocellular carcinoma and will control cervical cancer. Travellers can be protected against "exotic" diseases by appropriate vaccination. Vaccines are considered indispensable against bioterrorism. They can combat resistance to antibiotics in some pathogens. Noncommunicable diseases, such as ischaemic heart disease, could also be reduced by influenza vaccination. Immunization programmes have improved the primary care infrastructure in developing countries, lowered mortality in childhood and empowered women to better plan their families, with consequent health, social and economic benefits. Vaccination helps economic growth everywhere, because of lower morbidity and mortality. The annual return on investment in vaccination has been calculated to be between 12% and 18%. Vaccination leads to increased life expectancy. Long healthy lives are now recognized as a prerequisite for wealth, and wealth promotes health. Vaccines are thus efficient tools to reduce disparities in wealth and inequities in health.

Indexed as

Global HealthHealth PromotionHealth Status DisparitiesImmunization ProgramsPersons with DisabilitiesPreventive Health ServicesVaccinationAcute DiseaseChronic DiseaseHealth PolicyHumansMortalityPovertyPublic HealthSocioeconomic Factors

Identifiers

PMID18297169
PMCPMC2647387
OpenAlexW2162555339

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.