ArticleAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2008
A longitudinal study of risk factors for incident albuminuria in diabetic American Indians: the Strong Heart Study.
Article in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Reported sources of health inequities in Indigenous Peoples with chronic kidney disease: a systematic review of quantitative studies.BMC public health · 2021Pooled it
- Replication of the effect of SLC2A9 genetic variation on serum uric acid levels in American Indians.European journal of human genetics : EJHG · 2014Trial
- Dyslipidemia in American Indian Adolescents and Young Adults: Strong Heart Family Study.Journal of the American Heart Association · 2024Article
- Establishment and validation of the cut-off values of estimated glomerular filtration rate and urinary albumin-to-creatinine ratio for diabetic kidney disease: A multi-center, prospective cohort study.Frontiers in endocrinology · 2022Observational
- Atherogenic dyslipidemia and diabetic nephropathy.Journal of nephrology · 2020Review
- Sex difference in the incidence of microvascular complications in patients with type 2 diabetes mellitus: a prospective cohort study.Acta diabetologica · 2020Article
- Bidirectional and Temporal Association Between Hypertension and Microalbuminuria: A Longitudinal Study in Chinese Adults.Journal of the American Heart Association · 2018Article
- Insulin resistance, incident cardiovascular diseases, and decreased kidney function among nondiabetic American Indians: the Strong Heart Study.Diabetes care · 2013Article
- Association between fish consumption and nephropathy in American Indians--the Strong Heart Study.Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2012Article
- Predictors of incident albuminuria in the Framingham Offspring cohort.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2010Article
- Albuminuria among Alaska Natives--findings from the Genetics of Coronary Artery Disease in Alaska Natives (GOCADAN) study.Nephron. Clinical practice · 2010Article
- Risk factors for chronic kidney disease among American Indians and Alaska Natives--findings from the Kidney Early Evaluation Program.American journal of nephrology · 2009Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundThere have been no studies that use longitudinal data with more than 2 measurements and methods of longitudinal data analysis to identify risk factors for incident albuminuria over time more effectively. STUDY
designLongitudinal study. SETTINGS &
participantsA subgroup of participants in the Strong Heart Study, a population-based sample of American Indians, in central Arizona, Oklahoma, and North and South Dakota. Participants with diabetes without albuminuria were followed up for a mean of 4 years. PREDICTORS: Age, sex, study center, high-density lipoprotein and low-density lipoprotein cholesterol levels, triglyceride level, body mass index, systolic blood pressure, use of antihypertensive medication, smoking, hemoglobin A(1c) level, fasting glucose level, type of diabetes therapy, diabetes duration, plasma creatinine level, and urinary albumin-creatinine ratio (UACR). OUTCOMES & MEASUREMENTS: Albuminuria was defined as UACR of 30 mg/g or greater. Urine creatinine and albumin were measured by using the picric acid method and a sensitive nephelometric technique, respectively.
resultsOf 750 and 568 participants with diabetes without albuminuria and with normal plasma creatinine levels at the first and second examinations, 246 and 132 developed albuminuria by the second and third examinations, respectively. Incident albuminuria was predicted by baseline UACR, fasting glucose level, systolic blood pressure, plasma creatinine level, study center, current smoking, and use of angiotensin-converting enzyme inhibitors and antidiabetic medications. UACR of 10 to 30 mg/g increased the odds of developing albuminuria 2.7-fold compared with UACR less than 5 mg/g. LIMITATIONS: Single random morning urine specimen.
conclusionsMany risk factors identified for incident albuminuria can be modified. Control of blood pressure and glucose level, smoking cessation, and use of angiotensin-converting enzyme inhibitors may reduce the incidence of albuminuria.
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