Evidence map›Paper›PMID 18289593›Full record

ArticleThe Journal of urology2008

Late age (85 years or older) peak incidence of bladder cancer.

Matthew Schultzel, Sidney L Saltzstein, Tracy M Downs, Suzuho Shimasaki, Catherine Sanders, Georgia Robins Sadler

Open access · greenAbstract read
In one paragraph

Article in The Journal of urology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 81 citations in OpenAlex.

  1. Article
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  4. Review
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  8. Review
  9. Article
  10. Canadian Urological Association guideline on the management of non-muscle-invasive bladder cancer - Full-text.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2021
    Article
  11. Curative radiation therapy for very elderly bladder cancer patients with localized disease.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2018
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Understanding the limits of large datasets.Journal of cancer education : the official journal of the American Association for Cancer Education · 2012
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Matthew SchultzelRebecca and John Moores University of California-San Diego Cancer Center, San Diego, California 92093-0850, USA.
Sidney L Saltzstein
Tracy M Downs
Suzuho Shimasaki
Catherine Sanders
Georgia Robins Sadler
University of California, San Diego · USThe Ohio State University · USVA San Diego Healthcare System · US

Funding

VIRAL MALIGNANCYP30CA023100 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DIANE M SIMEONE · 1985 to 2026
$124.9M
San Diego EXPORT Comprehensive NCMHD Research CenterP60MD000220 · NIMHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DALEY, SANDRA P · 2002 to 2011
$11.0M
INCREASING DIVERSITY IN CANCER CONTROL RESEARCHR25CA078583 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KAGAWA-SINGER, MARJORIE LOUISE, PASICK, RENA JOY · 1998 to 2017
$5.5M
Cooperative Planning of the SDSU/UCSD Cancer PartnershipU56CA092081 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NAVARRO, ANA M · 2002 to 2007
$2.2M
UCSD Medical Student Summer Aging Research TrainingT35AG026757 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Benjamin Hyun Han, Ellen Eun-Ok Lee · 2005 to 2026
$2.2M
Cooperative Planning of the SDSU/UCSD Cancer Center Par*U56CA092079 · NCI · SAN DIEGO STATE UNIVERSITY · PI KLONOFF, ELIZABETH A · 2002 to 2007
$1.9M
COMMUNITY ONCOLOGISTS'CLINICAL TRIALS EDUCATION PROGRAMR25CA065745 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SADLER, GEORGIA ROBINS · 1995 to 2006
$1.6M
NCI NIH HHS 5 P30 CA023100-22NCI NIH HHS P30 CA023100NCI NIH HHS R25 CA065745NCI NIH HHS R25 CA078583NCI NIH HHS R25CA078583NCI NIH HHS R25CA65745NCI NIH HHS U56 CA092079NCI NIH HHS U56 CA092081NCI NIH HHS U56 CA92079NCI NIH HHS U56 CA92081NIA NIH HHS T35 AG026757NIA NIH HHS T35AG026757NIMHD NIH HHS P60 MD000220NIMHD NIH HHS P60MD00220
6 · The paper itself

Abstract

purposeWe examined the incidence rates of bladder cancer using California Cancer Registry data to determine if any trends exist. MATERIALS AND

methodsComplete records of the 55,159 cases of invasive bladder cancer were examined from the original 92,677 bladder cancer cases recorded in the California Cancer Registry between 1988 and 2004.

resultsCalifornia Cancer Registry data showed a universal late age peak in age specific incidence of bladder cancer in men and women, and across ethnic boundaries. The rate of annual increase in the percent of bladder cancer in individuals 85 years or older was increasing about 10 times as rapidly as the percent of the population that was 85 years or older (slope = 0.395 vs 0.0336). Furthermore, during all 17 years the proportion of patients 85 or older with bladder cancer was about twice that of patients with other cancers regardless of gender.

conclusionsCalifornia Cancer Registry data illustrate a peak in the incidence of bladder cancer in individuals 85 years or older. However, to our knowledge there is no known explanation for this late peak in bladder cancer. With the rate of bladder cancer in the population 85 years or older increasing at a rapid pace, it is critical to encourage investigators to include this age group as they continue to search for causative factors and genetic contributors to bladder cancer as well as effective treatments.

Indexed as

RegistriesAdultAgedAged, 80 and overAge FactorsCaliforniaFemaleHumansIncidenceMaleMiddle AgedUrinary Bladder Neoplasms

Identifiers

PMID18289593
PMCPMC3751586
OpenAlexW2108372442

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.