ReviewNeural plasticity2007
The importance of cognitive phenotypes in experimental modeling of animal anxiety and depression.
Review in Neural plasticity, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 55 citations in OpenAlex.
- Divergent behavioral strategies in Wistar and Wistar-Kyoto rats in a naturalistic task reveal mood disorder phenotypes.iScience · 2026Article
- Cross-species comparison of rodent and human decision-making in the Iowa Gambling Task in select neurological and psychiatric disorders: translational approach to examine age- and sex-specific effects of stress and corticolimbic perturbations.Frontiers in psychiatry · 2025Article
- Alloparenting by Helpers in Striped Hyena (Animals : an open access journal from MDPI · 2023Article
- Article
- Commentary: Establishing zebrafish as a model to study the anxiolytic effects of scopolamine.Frontiers in pharmacology · 2018Article
- Neuroplastic Correlates in the mPFC Underlying the Impairment of Stress-Coping Ability and Cognitive Flexibility in Adult Rats Exposed to Chronic Mild Stress during Adolescence.Neural plasticity · 2017Article
- The Increasing Importance of Gene-Based Analyses.PLoS genetics · 2016Review
- Commentary: Supplier-dependent differences in intermittent voluntary alcohol intake and response to naltrexone in Wistar rats.Frontiers in neuroscience · 2016Article
- Commentary: Ethological Evaluation of the Effects of Social Defeat Stress in Mice: Beyond the Social Interaction Ratio.Frontiers in behavioral neuroscience · 2016Article
- cGMP-dependent protein kinase type II knockout mice exhibit working memory impairments, decreased repetitive behavior, and increased anxiety-like traits.Neurobiology of learning and memory · 2014Article
- Where have I been? Where should I go? Spatial working memory on a radial arm maze in a rat model of depression.PloS one · 2013Article
- A glass full of optimism: enrichment effects on cognitive bias in a rat model of depression.Cognitive, affective & behavioral neuroscience · 2012Article
- The effects of acute treatment with escitalopram on the different stages of contextual fear conditioning are reversed by atomoxetine.Psychopharmacology · 2010Article
- Is subclinical anxiety an endophenotype for bipolar I patients? A study from a Costa Rican sample.Journal of affective disorders · 2010Article
- Emotional reactivity and cognitive performance in aversively motivated tasks: a comparison between four rat strains.Behavioral and brain functions : BBF · 2009Article
- Adenosine A(2A) receptors in psychopharmacology: modulators of behavior, mood and cognition.Current neuropharmacology · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
Abstract
Cognitive dysfunctions are commonly seen in many stress-related disorders, including anxiety and depression-the world's most common neuropsychiatric illnesses. Various genetic, pharmacological, and behavioral animal models have long been used to establish animal anxiety-like and depression-like phenotypes, as well as to assess their memory, learning, and other cognitive functions. Mounting clinical and animal evidences strongly supports the notion that disturbed cognitions represent an important pathogenetic factor in anxiety and depression, and may also play a role in integrating the two disorders within a common stress-precipitated developmental pathway. This paper evaluates why and how the assessment of cognitive and emotional domains may improve our understanding of animal behaviors via different high-throughput tests and enable a better translation of animal phenotypes into human brain disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.