ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2008
Inhibitory gating of vibrissal inputs in the brainstem.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 84 citations in OpenAlex.
- An elastic segment of the whisker shaft enables coding of the whisking phase via whisker torsion in rats and mice.Anatomical record (Hoboken, N.J. : 2007) · 2026Article
- Peri-head distance coding in the mouse brainstem.Neuron · 2026Article
- Organization and development of bilateral somatosensory feedback projections in mice.iScience · 2025Article
- Cholecystokinin neurons in the spinal trigeminal nucleus interpolaris regulate mechanically evoked predatory hunting in male mice.Nature communications · 2025Article
- Polysemia as a concept to understand the encoding of sensory information.Frontiers in neuroscience · 2025Article
- The Trigeminal Sensory System and Orofacial Pain.International journal of molecular sciences · 2024Review
- Direct and Indirect Nociceptive Input from the Trigeminal Dorsal Horn to Pain-Modulating Neurons in the Rostral Ventromedial Medulla.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Experience-dependent plasticity in early stations of sensory processing in mature brains: effects of environmental enrichment on dendrite measures in trigeminal nuclei.Brain structure & function · 2022Article
- Interactions of Whisking and Touch Signals in the Rat Brainstem.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Bidirectional learning in upbound and downbound microzones of the cerebellum.Nature reviews. Neuroscience · 2021Review
- Sensory Adaptation in the Whisker-Mediated Tactile System: Physiology, Theory, and Function.Frontiers in neuroscience · 2021Review
- Orally administered oxytocin alters brain activation and behaviors of pre-weaning mice.Hormones and behavior · 2020Article
- Cortical modulation of sensory flow during active touch in the rat whisker system.Nature communications · 2018Article
- Circuits in the rodent brainstem that control whisking in concert with other orofacial motor actions.Neuroscience · 2018Review
- Parallel Inhibitory and Excitatory Trigemino-Facial Feedback Circuitry for Reflexive Vibrissa Movement.Neuron · 2017Article
- Whisker-related afferents in superior colliculus.Journal of neurophysiology · 2016Article
- On-going computation of whisking phase by mechanoreceptors.Nature neuroscience · 2016Article
- Neonatal sensory nerve injury-induced synaptic plasticity in the trigeminal principal sensory nucleus.Experimental neurology · 2016Review
- Sensory Activity-Dependent and Sensory Activity-Independent Properties of the Developing Rodent Trigeminal Principal Nucleus.Developmental neuroscience · 2016Review
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Trigeminal sensory nuclei are the first processing stage in the vibrissal system of rodents. They feature separate populations of thalamic projecting cells and a rich network of intersubnuclear connections, so that what is conveyed to the cortex by each of the ascending pathways of vibrissal information depends on local transactions that occur in the brainstem. In the present study, we examined the nature of these intersubnuclear connections by combining electrolytic lesions with electrophysiological recordings, retrograde labeling with in situ hybridization, and anterograde labeling with immunoelectron microscopy. Together, these different approaches provide conclusive evidence that the principal trigeminal nucleus receives inhibitory GABAergic projections from the caudal sector of the interpolaris subnucleus, and excitatory glutamatergic projections from the caudalis subnucleus. These results raise the possibility that, by controlling the activity of intersubnuclear projecting cells, brain regions that project to the spinal trigeminal nuclei may take an active part in selecting the type of vibrissal information that is conveyed through the lemniscal pathway.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.