Evidence map›Paper›PMID 18287315›Full record

ArticleJournal of clinical microbiology2008

Impact of human bocavirus on children and their families.

Susanna Esposito, Samantha Bosis, Hubert G M Niesters, Elena Tremolati, Caterina Sabatini, Alessandro Porta, Emilio Fossali, Albert D M E Osterhaus, Nicola Principi

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Review
  2. Role of Human Bocavirus Respiratory Tract Infection in Hematopoietic Cell Transplant Recipients.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  3. Article
  4. Review
  5. Human Parvoviruses.Clinical microbiology reviews · 2017
    Review
  6. Human bocavirus: Current knowledge and future challenges.World journal of gastroenterology · 2016
    Review
  7. Article
  8. Article
  9. Article
  10. The role of infection in Kawasaki syndrome.The Journal of infection · 2013
    Review
  11. Article
  12. Review
  13. Article
  14. Viruses and bacteria in sputum samples of children with community-acquired pneumonia.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2012
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Human bocavirus in children: mono-detection, high viral load and viraemia are associated with respiratory tract infection.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Susanna EspositoInstitute of Pediatrics, University of Milan, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Via Commenda 9, 20122 Milano, Italy.
Samantha Bosis
Hubert G M Niesters
Elena Tremolati
Caterina Sabatini
Alessandro Porta
Emilio Fossali
Albert D M E Osterhaus
Nicola Principi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was planned to investigate the prevalence and clinical features of the illnesses associated with human bocavirus (hBoV) in children with acute disease. We prospectively enrolled all subjects aged less than 15 years attending an emergency room in Milan, Italy, on Wednesdays and Sundays between 1 November 2004 and 31 March 2005 for any acute medical reason, excluding surgical diseases and trauma. Nasopharyngeal swabs were collected at admission to detect hBoV; influenza A and B viruses; respiratory syncytial virus; human metapneumovirus; parainfluenza viruses 1, 2, 3, and 4; rhinovirus; adenovirus; and coronaviruses 229E, OC43, NL63, and HKU1 by real-time PCR. Among the 1,332 enrolled children, hBoV was the fifth most frequently detected virus (7.4%). The rate of hBoV coinfections with other viruses was significantly higher than for the other viruses (50.5% versus 27.5%; P < 0.0001). Eighty-nine of the 99 hBoV-positive children (89.9%) had a respiratory tract infection, and 10 (10.1%) had gastroenteritis. hBoV coinfections had a significantly greater clinical and socioeconomic impact on the infected children and their households than hBoV infection alone. In conclusion, these findings show that the role of hBoV infection alone seems marginal in children attending an emergency room for acute disease; its clinical and socioeconomic importance becomes relevant only when it is associated with other viruses.

Indexed as

Acute DiseaseAdolescentBocavirusChildChild, PreschoolExanthemaFemaleFeverGastroenteritisHumansInfantInfant, NewbornItalyMaleParvoviridae InfectionsPrevalence

Identifiers

PMID18287315
PMCPMC2292932

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.