ArticleProceedings of the National Academy of Sciences of the United States of America2008
The Foldback-like element Galileo belongs to the P superfamily of DNA transposons and is widespread within the Drosophila genus.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed.
- Satellite DNAs in Drosophila koepferae (repleta group) reveal patterns of origin, chromosomal organization, transcription, and turnover in the buzzatii cluster.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2026Article
- Evolutionary History of the DD41D Family of Tc1/Mariner Transposons in Two Mayetiola Species.Biochemical genetics · 2025Article
- Differential DNA methylation in response to host environment changes in Drosophila gouveai.Genetica · 2025Article
- Horizontal transfer and the widespread presence of Galileo transposons in Drosophilidae (Insecta: Diptera).Genetics and molecular biology · 2024Article
- Adaptation, ancestral variation and gene flow in a 'Sky Island' Drosophila species.Molecular ecology · 2021Article
- Structural and functional liaisons between transposable elements and satellite DNAs.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2015Review
- Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution.G3 (Bethesda, Md.) · 2015Article
- Structural and sequence diversity of the transposon Galileo in the Drosophila willistoni genome.BMC genomics · 2014Article
- Tetris is a foldback transposon that provided the building blocks for an emerging satellite DNA of Drosophila virilis.Genome biology and evolution · 2014Article
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- Striking structural dynamism and nucleotide sequence variation of the transposon Galileo in the genome of Drosophila mojavensis.Mobile DNA · 2013Article
- A divergent P element and its associated MITE, BuT5, generate chromosomal inversions and are widespread within the Drosophila repleta species group.Genome biology and evolution · 2013Article
- General survey of hAT transposon superfamily with highlight on hobo element in Drosophila.Genetica · 2012Article
- Gene alterations at Drosophila inversion breakpoints provide prima facie evidence for natural selection as an explanation for rapid chromosomal evolution.BMC genomics · 2012Article
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- Phantom, a new subclass of Mutator DNA transposons found in insect viruses and widely distributed in animals.Genetics · 2010Article
- The transposon Galileo generates natural chromosomal inversions in Drosophila by ectopic recombination.PloS one · 2009Article
- Evolution of Tom, 297, 17.6 and rover retrotransposons in Drosophilidae species.Molecular genetics and genomics : MGG · 2009Article
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3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Galileo is the only transposable element (TE) known to have generated natural chromosomal inversions in the genus Drosophila. It was discovered in Drosophila buzzatii and classified as a Foldback-like element because of its long, internally repetitive, terminal inverted repeats (TIRs) and lack of coding capacity. Here, we characterized a seemingly complete copy of Galileo from the D. buzzatii genome. It is 5,406 bp long, possesses 1,229-bp TIRs, and encodes a 912-aa transposase similar to those of the Drosophila melanogaster 1360 (Hoppel) and P elements. We also searched the recently available genome sequences of 12 Drosophila species for elements similar to Dbuz\Galileo by using bioinformatic tools. Galileo was found in six species (ananassae, willistoni, peudoobscura, persimilis, virilis, and mojavensis) from the two main lineages within the Drosophila genus. Our observations place Galileo within the P superfamily of cut-and-paste transposons and extend considerably its phylogenetic distribution. The interspecific distribution of Galileo indicates an ancient presence in the genus, but the phylogenetic tree built with the transposase amino acid sequences contrasts significantly with that of the species, indicating lineage sorting and/or horizontal transfer events. Our results also suggest that Foldback-like elements such as Galileo may evolve from DNA-based transposon ancestors by loss of the transposase gene and disproportionate elongation of TIRs.
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