ArticleAnatomical record (Hoboken, N.J. : 2007)2008
Optimization of volumetric computed tomography for skeletal analysis of model genetic organisms.
Article in Anatomical record (Hoboken, N.J. : 2007), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Unveiling vertebrate development dynamics in frog Xenopus laevis using micro-CT imaging.GigaScience · 2024Article
- Effect of curvature on wetting and dewetting of proboscises of butterflies and moths.Royal Society open science · 2018Article
- An optimized method for delivering flow tracer particles to intravital fluid environments in the developing zebrafish.Zebrafish · 2012Article
- Normalized shape and location of perturbed craniofacial structures in the Xenopus tadpole reveal an innate ability to achieve correct morphology.Developmental dynamics : an official publication of the American Association of Anatomists · 2012Article
- 3-dimensional imaging modalities for phenotyping genetically engineered mice.Veterinary pathology · 2012Review
- Time-gated optical projection tomography allows visualization of adult zebrafish internal structures.PloS one · 2012Article
- The Digital Fish Library: using MRI to digitize, database, and document the morphological diversity of fish.PloS one · 2012Article
- Whole-animal imaging, gene function, and the Zebrafish Phenome Project.Current opinion in genetics & development · 2011Review
- Conditional ablation of Pten in osteoprogenitors stimulates FGF signaling.Development (Cambridge, England) · 2011Article
- Motion-artifact-free in vivo imaging utilizing narcotized avian embryos in ovo.Molecular imaging and biology · 2011Article
- Tbx22null mice have a submucous cleft palate due to reduced palatal bone formation and also display ankyloglossia and choanal atresia phenotypes.Human molecular genetics · 2009Article
- Finfish and aquatic invertebrate pathology resources for now and the future.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
Forward and reverse genetics now allow researchers to understand embryonic and postnatal gene function in a broad range of species. Although some genetic mutations cause obvious morphological change, other mutations can be more subtle and, without adequate observation and quantification, might be overlooked. For the increasing number of genetic model organisms examined by the growing field of phenomics, standardized but sensitive methods for quantitative analysis need to be incorporated into routine practice to effectively acquire and analyze ever-increasing quantities of phenotypic data. In this study, we present platform-independent parameters for the use of microscopic x-ray computed tomography (microCT) for phenotyping species-specific skeletal morphology of a variety of different genetic model organisms. We show that microCT is suitable for phenotypic characterization for prenatal and postnatal specimens across multiple species.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.