ArticleJournal of neurology2008
Radiosurgery of brain arteriovenous malformations in children.
Article in Journal of neurology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Stereotactic radiosurgery treatment of pediatric arteriovenous malformations: a PRISMA systematic review and meta-analysis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Pooled it
- What is the best therapeutic approach to a pediatric patient with a deep-seated brain AVM?Neurosurgical review · 2019Pooled it
- Obstructive hydrocephalus due to high-volume liquid embolic agent embolization for management of pediatric arteriovenous malformations: illustrative case.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Multimodal Treatment of Pediatric Ruptured Brain Arteriovenous Malformations: A Single-Center Study.Children (Basel, Switzerland) · 2021Article
- Comparison of the Long-term Efficacy and Safety of Gamma Knife Radiosurgery for Arteriovenous Malformations in Pediatric and Adult Patients.Neurologia medico-chirurgica · 2018Article
- Clinical outcomes and radiosurgical considerations for pediatric arteriovenous malformation: influence of clinical features on obliteration rate.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017Article
- Gamma Knife radiosurgery for arteriovenous malformations in pediatric patients.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2014Article
- Safety and efficacy using a detachable tip microcatheter in the embolization of pediatric arteriovenous malformations.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2014Article
- Angiographic features help predict outcome after stereotactic radiosurgery for the treatment of pediatric arteriovenous malformations.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2014Article
- Stereotactic linac radiosurgery and hypofractionated stereotactic radiotherapy for pediatric arteriovenous malformations of the brain: experiences of a single institution.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2013Article
- The predictive value of 3D time-of-flight MR angiography in assessment of brain arteriovenous malformation obliteration after radiosurgery.AJNR. American journal of neuroradiology · 2012Article
- Clinico-radiological outcomes following gamma knife radiosurgery for pediatric arteriovenous malformations.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2011Article
- Stereotactic radiotherapy and radiosurgery in pediatric patients: analysis of indications and outcome.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2010Article
- Pediatric Intracranial Arteriovenous Malformation: Long-Term Outcomes with Linear Accelerator (LINAC)-Based Radiosurgery.Advances in radiation oncologyArticle
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe authors describe their experience in treating 22 children with a single brain arteriovenous malformation (bAVM) using a dedicated LINAC stereotactic radiosurgery unit.
methodsThe findings of 22 consecutive patients < or = 18 years of age who underwent radiosurgery for a single bAVM and with at least 24 months of follow-up, or earlier proven obliteration,were reviewed. The median age at radiosurgery was 13.8 years,with a hemorrhagic presentation in 86%. Median bAVM-volume was 1.8 ml, with a median prescribed marginal dose of 19.0 Gy.
resultsThe crude complete obliteration-rate was 68% (n = 15) after a median follow-up of 24 months. The actuarial obliteration- rate was 45 % after two years and 64 % after three years. Patients with a radiosurgery-based AVM score < or = 1 more frequently had an excellent outcome than patients with a bAVM score > 1 (71% vs. 20%, P = 0.12), as well as an increased obliteration rate (P = 0.03) One patient died from a bAVM-related hemorrhage 27 months after radiosurgery, representing a postradiosurgery hemorrhage rate of 1.3%/year for the complete followup interval. Overall outcome was good to excellent in 68% (n = 15). Radiation-induced changes on MR imaging were seen in 36% (n = 8) after a median interval of 12.5 months, resulting in deterioration of pre-existing neurological symptoms in one patient.
conclusionsRadiosurgery is a relatively effective, minimally invasive treatment for small bAVMs in children. The rebleeding rate is low, provided that known predilection places for bleeding had been endovascularly eliminated.Our overall results compare unfavourably to recent pediatric microsurgical series, although comparison between series remains imprecise. Nevertheless, when treatment is indicated in a child with a bAVM that is amenable to both microsurgery or radiosurgery, microsurgery should carefully be advocated over radiosurgery, because of its immediate risk reduction.
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