Evidence map›Paper›PMID 18281407›Full record

Trial reportThe American journal of psychiatry2008

Systems Training for Emotional Predictability and Problem Solving (STEPPS) for outpatients with borderline personality disorder: a randomized controlled trial and 1-year follow-up.

Nancee Blum, Don St John, Bruce Pfohl, Scott Stuart, Brett McCormick, Jeff Allen, Stephan Arndt, Donald W Black

Erratum issued 2 registry-linked trialsAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in The American journal of psychiatry, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 2 registered trials, which are not on this map. Cited by 83 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 7 pooled it
29.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03418675 phase2completednot on this mapstarted 2018, after this paper: background citation

A Double-Blind, Placebo-Controlled Study of Brexpiprazole in the Treatment of Borderline Personality Disorder.

TypeinterventionalSponsorUniversity of ChicagoRan2018 to 2021Enrolled80ConditionsBorderline Personality DisorderArmsRexulti, Placebo
NCT05399498 phase2completednot on this mapstarted 2023, after this paper: background citation

An Open Label Study of Single-Dose Psilocybin for Major Depressive Disorder With Co-occurring Borderline Personality Disorder

TypeinterventionalSponsorUniversity of ChicagoRan2023 to 2025Enrolled9ConditionsBorderline Personality Disorder, Major Depressive DisorderArmsPsilocybin
3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 7 syntheses or guidelines pooled it, 408 citations in OpenAlex.

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  4. Psychological interventions for antisocial personality disorder.The Cochrane database of systematic reviews · 2020
    Pooled it
  5. Impact of Psychotherapy on Psychosocial Functioning in Borderline Personality Disorder Patients.International journal of environmental research and public health · 2020
    Pooled it
  6. Psychological therapies for people with borderline personality disorder.The Cochrane database of systematic reviews · 2020
    Pooled it
  7. Psychological therapies for people with borderline personality disorder.The Cochrane database of systematic reviews · 2012
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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Nancee BlumDepartment of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.
Don St John
Bruce Pfohl
Scott Stuart
Brett McCormick
Jeff Allen
Stephan Arndt
Donald W Black
University of Iowa · US

Funding

A Cognitive Group Treatment for Borderline OutpatientsR01MH063746 · NIMH · UNIVERSITY OF IOWA · PI BLACK, DONALD W. · 2002 to 2005
$1.8M
NIMH NIH HHS MH-63746NIMH NIH HHS R01 MH063746
6 · The paper itself

Abstract

objectiveSystems Training for Emotional Predictability and Problem Solving (STEPPS) is a 20-week manual-based group treatment program for outpatients with borderline personality disorder that combines cognitive behavioral elements and skills training with a systems component. The authors compared STEPPS plus treatment as usual with treatment as usual alone in a randomized controlled trial.

methodSubjects with borderline personality disorder were randomly assigned to STEPPS plus treatment as usual or treatment as usual alone. Total score on the Zanarini Rating Scale for Borderline Personality Disorder was the primary outcome measure. Secondary outcomes included measures of global functioning, depression, impulsivity, and social functioning; suicide attempts and self-harm acts; and crisis utilization. Subjects were followed 1 year posttreatment. A linear mixed-effects model was used in the analysis.

resultsData pertaining to 124 subjects (STEPPS plus treatment as usual [N=65]; treatment as usual alone [N=59]) were analyzed. Subjects assigned to STEPPS plus treatment as usual experienced greater improvement in the Zanarini Rating Scale for Borderline Personality Disorder total score and subscales assessing affective, cognitive, interpersonal, and impulsive domains. STEPPS plus treatment as usual also led to greater improvements in impulsivity, negative affectivity, mood, and global functioning. These differences yielded moderate to large effect sizes. There were no differences between groups for suicide attempts, self-harm acts, or hospitalizations. Most gains attributed to STEPPS were maintained during follow-up. Fewer STEPPS plus treatment as usual subjects had emergency department visits during treatment and follow-up. The discontinuation rate was high in both groups.

conclusionsSTEPPS, an adjunctive group treatment, can deliver clinically meaningful improvements in borderline personality disorder-related symptoms and behaviors, enhance global functioning, and relieve depression.

Indexed as

Ambulatory CareAdultBorderline Personality DisorderCognitive Behavioral TherapyEmotionsFemaleFollow-Up StudiesHumansMaleManuals as TopicOutcome Assessment, Health CarePatient Education as TopicPlacebosProblem SolvingPsychiatric Status Rating ScalesPsychotherapyPlacebos

Identifiers

PMID18281407
PMCPMC3608469
OpenAlexW2126038180

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.