ArticleJournal of bacteriology2008
An extracellular glycoprotein is implicated in cell-cell contacts in the toxic cyanobacterium Microcystis aeruginosa PCC 7806.
Article in Journal of bacteriology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 71 citations in OpenAlex.
- A family of tubular pili from harmful algal bloom forming cyanobacterium Microcystis aeruginosa.Nature communications · 2025Article
- Article
- Microcystin shapes theISME communications · 2025Article
- Closed circular genome sequence of aMicrobiology resource announcements · 2023Article
- Cyanotoxins and Other Bioactive Compounds from the Pasteur Cultures of Cyanobacteria (PCC).Toxins · 2023Review
- The increasing role of structural proteomics in cyanobacteria.Essays in biochemistry · 2023Review
- Hydrodynamic conditions affect the proteomic profile of marine biofilms formed by filamentous cyanobacterium.NPJ biofilms and microbiomes · 2022Article
- Evaluation of Microalgae Antiviral Activity and Their Bioactive Compounds.Antibiotics (Basel, Switzerland) · 2021Review
- Diel Variations of Extracellular Microcystin Influence the Subcellular Dynamics of RubisCO inMicroorganisms · 2021Article
- Article
- Diverse light responses of cyanobacteria mediated by phytochrome superfamily photoreceptors.Nature reviews. Microbiology · 2019Review
- Moving towards adaptive management of cyanotoxin-impaired water bodies.Microbial biotechnology · 2016Review
- Proteomic approaches in research of cyanobacterial photosynthesis.Photosynthesis research · 2015Review
- Biosynthesis and function of extracellular glycans in cyanobacteria.Life (Basel, Switzerland) · 2015Review
- The Anabaena sp. PCC 7120 Exoproteome: Taking a Peek outside the Box.Life (Basel, Switzerland) · 2015Article
- The putative eukaryote-like O-GlcNAc transferase of the cyanobacterium Synechococcus elongatus PCC 7942 hydrolyzes UDP-GlcNAc and is involved in multiple cellular processes.Journal of bacteriology · 2015Article
- Role of environmental factors and toxic genotypes in the regulation of microcystins-producing cyanobacterial blooms.Microbial ecology · 2014Article
- Interpreting the possible ecological role(s) of cyanotoxins: compounds for competitive advantage and/or physiological aide?Marine drugs · 2013Review
- The languages spoken in the water body (or the biological role of cyanobacterial toxins).Frontiers in microbiology · 2012Article
- Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microcystins are the most common cyanobacterial toxins found in freshwater lakes and reservoirs throughout the world. They are frequently produced by the unicellular, colonial cyanobacterium Microcystis aeruginosa; however, the role of the peptide for the producing organism is poorly understood. Differences in the cellular aggregation of M. aeruginosa PCC 7806 and a microcystin-deficient Delta mcyB mutant guided the discovery of a surface-exposed protein that shows increased abundance in PCC 7806 mutants deficient in microcystin production compared to the abundance of this protein in the wild type. Mass spectrometric and immunoblot analyses revealed that the protein, designated microcystin-related protein C (MrpC), is posttranslationally glycosylated, suggesting that it may be a potential target of a putative O-glycosyltransferase of the SPINDLY family encoded downstream of the mrpC gene. Immunofluorescence microscopy detected MrpC at the cell surface, suggesting an involvement of the protein in cellular interactions in strain PCC 7806. Further analyses of field samples of Microcystis demonstrated a strain-specific occurrence of MrpC possibly associated with distinct Microcystis colony types. Our results support the implication of microcystin in the colony specificity of and colony formation by Microcystis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.