ArticlePediatric nephrology (Berlin, Germany)2008
Antenatally detected urinary tract abnormalities: more detection but less action.
Article in Pediatric nephrology (Berlin, Germany), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.
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Who cites it
61 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical practice guideline on pregnancy and renal disease.BMC nephrology · 2019Guideline
- Genetic diagnosis in fetal hydronephrosis: assessment using chromosomal microarray analysis and whole-genome sequencing.Human genomics · 2026Article
- Triple-bolus CT urography: an optimized approach for vascular assessment in ureteropelvic junction obstruction.BJR open · 2026Article
- Predicting congenital anomalies of the kidney and urinary tract (CAKUT) in prenatal hydronephrosis via machine learning.World journal of urology · 2025Article
- Longitudinal image-based prediction of surgical intervention in infants with hydronephrosis using deep learning: Is a single ultrasound enough?PLOS digital health · 2025Article
- Increased kidney length in mild urinary tract dilatation is a significant prognostic factor for non-resolution.Pediatric nephrology (Berlin, Germany) · 2025Article
- Development of LncRNA Biomarkers in Extracellular Vesicle of Amniotic Fluid Associated with Antenatal Hydronephrosis.Biomedicines · 2025Article
- Swiss Consensus on Prenatal and Early Postnatal Urinary Tract Dilation: Practical Approach and When to Refer.Children (Basel, Switzerland) · 2024Review
- Antenatally detected urinary tract dilatation: a pediatric nephrologist's point of view.Childhood kidney diseases · 2024Review
- Article
- Antenatally detected urinary tract dilatation: long-term outcome.Pediatric nephrology (Berlin, Germany) · 2023Review
- The Diagnostic Efficacy of and Requirement for Postnatal Ultrasonography Screening for Congenital Anomalies of the Kidney and Urinary Tract.Diagnostics (Basel, Switzerland) · 2023Article
- Degree of kidney injury due to artificial pelvic-ureteric junction obstruction with level of neutrophil gelatinase-associated lipocalin, interleukin 18, and histopathological descriptions in Wistar: experimental research.Annals of medicine and surgery (2012) · 2023Article
- Management dilemma in pelvi-ureteric junction obstruction: is transit time the answer?Pediatric surgery international · 2023Article
- Review
- Diagnostic accuracy of an interdisciplinary tertiary center evaluation in children referred for suspected congenital anomalies of the kidney and urinary tract on fetal ultrasound - a retrospective outcome analysis.Pediatric nephrology (Berlin, Germany) · 2021Article
- Is the prognosis of congenital single functioning kidney benign? A population-based study.Pediatric nephrology (Berlin, Germany) · 2021Article
- Retrospective evaluation of the pediatric multicystic dysplastic kidney patients: experience of two centers from southeastern TurkeyTurkish journal of medical sciences · 2021Article
- A Retrospective Analysis to Evaluate Role of the New UTD Classification System in Prenatal Prediction of Severity and Postnatal Outcome in Antenatally Diagnosed Urinary Tract Dilatation Abnormalities.Journal of obstetrics and gynaecology of India · 2021Article
- Management of antenatal hydronephrosis.Pediatric nephrology (Berlin, Germany) · 2020Review
1 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We present the findings of a prospective cohort study of babies born with antenatally detected urinary tract abnormalities (AUTAs) between 1999-2003 and compare the outcomes with those of an earlier cohort born between 1989 and 1993. All infants with a fetal anteroposterior renal pelvic diameter (APRPD) > or =7 mm in the third trimester or other urinary tract abnormality underwent a detailed postnatal ultrasound scan and other investigations as indicated. The incidence of AUTAs was significantly greater in the more recent cohort (7.6/1000 vs. 3/1000 live births; p<0.05). Of the 350 infants on which we had data, 48.6% (170/350) were in the non-specific dilatation (NSD) category, and vesicoureteric reflux (VUR) was detected in 12%. Restricting investigations to those who had an APRPD > or =10 mm at >30 weeks of gestation could have reduced the number with NSD in the more recent cohort (26/115; 25%), but 25% of those with pelviureteric junction hold-up and 50% with VUR would have been missed. Significantly fewer patients in the more recent cohort underwent surgery (7 vs. 21%; p<0.001). There is a trend towards larger APRPDs on third trimester scans being associated with more significant pathology, but there is a lot of clinical overlap. The study highlights the need for cautious antenatal counselling combined with an assurance to prospective parents that postnatal investigations will be performed in a stepwise manner based on the initial postnatal ultrasound scan and clinical findings.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.