ReviewFrontiers in neuroendocrinology2008
Anabolic-androgenic steroid dependence? Insights from animals and humans.
Review in Frontiers in neuroendocrinology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 149 citations in OpenAlex.
- The effect of a dopamine antagonist on conditioning of sexual arousal in women.Psychopharmacology · 2016Trial
- Anabolic-androgenic steroid use disorder: case for recognition as a substance use disorder with specific diagnostic criteria.The British journal of psychiatry : the journal of mental science · 2026Review
- Psychological traits associated with anabolic androgenic steroid use and dependence: an exploratory cross-sectional study among female athletes.BMC women's health · 2025Article
- Development and validation of dependence and craving measures specific to athletes who use anabolic-androgenic steroids.Frontiers in psychology · 2024Article
- Innovative Detection of Testosterone Esters in Camel Hair: Unravelling the Mysteries of Dromedary Endocrinology.Molecules (Basel, Switzerland) · 2023Article
- Gendered perspectives on women's anabolic-androgenic steroid (AAS) usage practices.Harm reduction journal · 2023Article
- The Uses of Anabolic Androgenic Steroids Among Athletes; Its Positive and Negative Aspects- A Literature Review.Journal of multidisciplinary healthcare · 2023Review
- Sex differences in opioid receptor mediated effects: Role of androgens.Neuroscience and biobehavioral reviews · 2022Review
- Effects of Exogenous Androgens on Platelet Activity and Their Thrombogenic Potential in Supraphysiological Administration: A Literature Review.Journal of clinical medicine · 2021Review
- Sex and the dopaminergic system: Insights from addiction studies.Handbook of clinical neurology · 2020Review
- Neuroendocrinology of reward in anorexia nervosa and bulimia nervosa: Beyond leptin and ghrelin.Molecular and cellular endocrinology · 2019Review
- Anabolic androgenic steroid dependence is associated with impaired emotion recognition.Psychopharmacology · 2019Article
- The Proximate Causes of Waorani Warfare.Human nature (Hawthorne, N.Y.) · 2019Article
- Structural brain characteristics of anabolic-androgenic steroid dependence in men.Addiction (Abingdon, England) · 2019Article
- Neuropsychiatric and Behavioral Involvement in AAS Abusers. A Literature Review.Medicina (Kaunas, Lithuania) · 2019Review
- Defining the Construct of Synthetic Androgen Intoxication: An Application of General Brain Arousal.Frontiers in psychology · 2018Article
- Behavioral cross-sensitization between testosterone and fenproporex in adolescent and adult rats.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2017Article
- The role of neuropeptide-Y in nandrolone decanoate-induced attenuation of antidepressant effect of exercise.PloS one · 2017Article
- Anabolic-androgenic steroids decrease dendritic spine density in the nucleus accumbens of male rats.Neuroscience · 2016Article
- Mad men, women and steroid cocktails: a review of the impact of sex and other factors on anabolic androgenic steroids effects on affective behaviors.Psychopharmacology · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Anabolic-androgenic steroids (AAS) are drugs of abuse. They are taken in large quantities by athletes and others to increase performance, with negative health consequences. As a result, in 1991 testosterone and related AAS were declared controlled substances. However, the relative abuse and dependence liability of AAS have not been fully characterized. In humans, it is difficult to separate the direct psychoactive effects of AAS from reinforcement due to their systemic anabolic effects. However, using conditioned place preference and self-administration, studies in animals have demonstrated that AAS are reinforcing in a context where athletic performance is irrelevant. Furthermore, AAS share brain sites of action and neurotransmitter systems in common with other drugs of abuse. In particular, recent evidence links AAS with opioids. In humans, AAS abuse is associated with prescription opioid use. In animals, AAS overdose produces symptoms resembling opioid overdose, and AAS modify the activity of the endogenous opioid system.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.