Evidence map›Paper›PMID 18275910›Full record

ReviewDrug discovery today2008

Ophthalmic light sensitive nanocarrier systems.

Jennifer G Christie, Uday B Kompella

Open access · greenAbstract readReview
In one paragraph

Review in Drug discovery today, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 71 citations in OpenAlex.

  1. Review
  2. Review
  3. Light-responsive biomaterials for ocular drug delivery.Drug delivery and translational research · 2023
    Review
  4. Review
  5. Review
  6. ISOPTJournal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics · 2019
    Article
  7. Article
  8. Review
  9. Nanocrystal for ocular drug delivery: hope or hype.Drug delivery and translational research · 2016
    Review
  10. Intraocular Implants for the Treatment of Autoimmune Uveitis.Journal of functional biomaterials · 2015
    Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jennifer G ChristieDepartment of Pharmaceutical Sciences, 985840 Nebraska Medical Center, Omaha, NE 68198-5840, United States.
Uday B Kompella
Nebraska Medical Center · US

Funding

Transscleral Drug Delivery for Retinal DisordersR24EY017045 · NEI · EMORY UNIVERSITY · PI EDELHAUSER, HENRY FRANCIS · 2006 to 2010
$6.9M
Delivery of LEDGF for retinal degenerative disordersR21EY017360 · NEI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI KOMPELLA, UDAY B · 2007 to 2008
$395k
NEI NIH HHS R21 EY017360NEI NIH HHS R24 EY017045
6 · The paper itself

Abstract

The eye is afflicted by chronic vision debilitating neovascular disorders, such as age-related macular degeneration, proliferative diabetic retinopathy, and corneal angiogenesis. Photodynamic therapy (PDT) is an innovative, evolving approach for treating neovascular diseases of the eye. PDT refers to the process of activating a light sensitive agent or carrier with non-thermal light to induce chemical reactions that ameliorate a pathological condition. Key components of PDT include a photosensitizer, a colloidal carrier or formulation and a light source. This article summarizes currently available clinical PDTs, desirable features of PDTs and photosensitizers, useful light sources for PDT and investigational nanosystems, and colloidal carriers for PDT.

Indexed as

Chronic DiseaseDrug CarriersEye DiseasesHumansModels, AnatomicNanostructuresPhotochemotherapyPhotosensitizing AgentsDrug CarriersPhotosensitizing Agents

Identifiers

PMID18275910
PMCPMC2274995
OpenAlexW1969740530

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.