Evidence map›Paper›PMID 18275522›Full record

ReviewThe British journal of dermatology2008

Skin microbiota: a source of disease or defence?

A L Cogen, V Nizet, R L Gallo

Abstract readReview
In one paragraph

Review in The British journal of dermatology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 357 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
357citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

357 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Hand Sanitizers: A Review on Formulation Aspects, Adverse Effects, and Regulations.International journal of environmental research and public health · 2020
    Pooled it
  4. Article
  5. Article
  6. Review
  7. Strain-level genomic analysis ofMicrobiology spectrum · 2026
    Article
  8. Observational
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  10. Review
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  18. Article
  19. Review
  20. Review

297 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

A L CogenDepartment of Bioengineering, Division of Dermatology, School of Medicine, University of California, San Diego, CA, USA.
V Nizet
R L Gallo

Funding

Cathelicidins in Skin ImmunityR01AI052453 · NIAID · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI GALLO, RICHARD L, NIZET, VICTOR · 2002 to 2017
$5.3M
Cathelicidin in Skin ImmunityR37AI052453 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Richard L Gallo, Victor Nizet · 2019 to 2026
$4.6M
Proteolysis and Skin AntimicrobialsR01AR052728 · NIAMS · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI GALLO, RICHARD L · 2006 to 2015
$3.3M
NIAID NIH HHS R01 AI052453NIAID NIH HHS R37 AI052453NIAMS NIH HHS R01 AR052728
6 · The paper itself

Abstract

Microbes found on the skin are usually regarded as pathogens, potential pathogens or innocuous symbiotic organisms. Advances in microbiology and immunology are revising our understanding of the molecular mechanisms of microbial virulence and the specific events involved in the host-microbe interaction. Current data contradict some historical classifications of cutaneous microbiota and suggest that these organisms may protect the host, defining them not as simple symbiotic microbes but rather as mutualistic. This review will summarize current information on bacterial skin flora including Staphylococcus, Corynebacterium, Propionibacterium, Streptococcus and Pseudomonas. Specifically, the review will discuss our current understanding of the cutaneous microbiota as well as shifting paradigms in the interpretation of the roles microbes play in skin health and disease.

Indexed as

Corynebacterium diphtheriaeFemaleGram-Positive Bacterial InfectionsGram-Positive CocciHumansMaleMetagenomeMicrobial ViabilityPropionibacterium acnesSkin

Identifiers

PMID18275522
PMCPMC2746716

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.