Evidence map›Paper›PMID 18274881›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2008

EuroQol EQ-5D and condition-specific measures of health outcome in women with urinary incontinence: reliability, validity and responsiveness.

Kirstie L Haywood, Andrew M Garratt, Ranjit Lall, Jan Fereday Smith, Sarah E Lamb

Abstract readValidation Study
PubMed Publisher
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Bladder training for treating overactive bladder in adults.The Cochrane database of systematic reviews · 2023
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Assessment of the Relative Performance of the EQ-5D-3L, ICIQ-UI SF and POP-SS Using Data from the OPAL Trial.International journal of environmental research and public health · 2022
    Trial
  5. Trial
  6. Trial
  7. The effect of weight loss on changes in health-related quality of life among overweight and obese women with urinary incontinence.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2012
    Trial
  8. Trial
  9. Exploring the impact of changes in neurogenic urinary incontinence frequency and condition-specific quality of life on preference-based outcomes.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2010
    Trial
  10. Exploring the content validity of the EQ-5D-5L and four bolt-ons (skin irritation, self-confidence, sleep, social relationships) in atopic dermatitis and chronic urticaria.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  11. Observational
  12. The estimation of a preference-based single index for the IBS-QoL by mapping to the EQ-5D-5L in patients with irritable bowel syndrome.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. OnabotulinumtoxinA in the treatment of overactive bladder: a cost-effectiveness analysis versus best supportive care in England and Wales.The European journal of health economics : HEPAC : health economics in prevention and care · 2016
    Article
  19. The validity and responsiveness of the ICECAP-A capability-well-being measure in women with irritative lower urinary tract symptoms.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2016
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kirstie L HaywoodRoyal College of Nursing Research Institute, School of Health and Social Studies, Warwick University, Coventry CV4 5AL, UK. kirstie.haywood@rcn.org.uk
Andrew M Garratt
Ranjit Lall
Jan Fereday Smith
Sarah E Lamb

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the measurement properties of the EuroQoL EQ-5D and two condition-specific patient-reported outcome measures--the Symptom Severity Index (SSI) and the Urinary Incontinence-Specific Quality of Life instrument (I-QoL)--in women with urinary incontinence.

methodsA questionnaire comprising all instruments was completed by women taking part in a clinical trial of physiotherapy for urinary incontinence. Follow-up questionnaires were at 6 weeks and 5 months. Data quality, internal consistency reliability, validity and responsiveness were assessed.

resultsOne hundred and seventy-four patients taking part in the clinical trial completed the questionnaire. Instruments had low levels of missing data. The EQ-5D had a large ceiling effect and poor responsiveness. The SSI had poor validity and responsiveness. The I-QoL had levels of reliability that supported application in group assessment, and in some cases, individual assessment, and good evidence of validity. The I-QoL was the most responsive instrument at both 6 weeks and 5 months.

conclusionThe I-QoL was the best performing instrument and is recommended as a continence-specific measure of quality of life in a clinical trial setting. The SSI and EQ-5D are not recommended. Alternative generic instruments, which support economic evaluation, require further evaluation in trials of female urinary incontinence.

Indexed as

Health StatusFemaleHealth Status IndicatorsHumansMiddle AgedPsychological TestsPsychometricsQuality of LifeReproducibility of ResultsSeverity of Illness IndexSurveys and QuestionnairesTreatment OutcomeUrinary Incontinence

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.