ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2008
Emergence of MRSA in positive blood cultures from patients with febrile neutropenia--a cause for concern.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Evaluation of Febrile Neutropenia in Hospitalized Patients with Neoplasia Undergoing Chemotherapy.Microorganisms · 2023Article
- Acute Oncologic Complications: Clinical-Therapeutic Management in Critical Care and Emergency Departments.Current oncology (Toronto, Ont.) · 2023Review
- Antimicrobial Stewardship in Hematological Patients at the intensive care unit: a global cross-sectional survey from the Nine-i Investigators Network.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020Article
- Diagnosis and Management of Oncologic Emergencies.The western journal of emergency medicine · 2019Review
- [A multicenter, retrospective study of pathogenic bacteria distribution and drug resistance in febrile neutropenic patients with hematological diseases in Shanghai].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2017Article
- Antibacterial Resistance in Patients with Hematopoietic Stem Cell Transplantation.Mediterranean journal of hematology and infectious diseases · 2017Review
- Evaluation of febrile neutropenic episodes in adult patients with solid tumors.Molecular and clinical oncology · 2016Article
- Daptomycin for Gram-positive Infections in Patients with Neutropenia: Clinical Experience from a European Outcomes Registry.Advances in therapy · 2015Article
- Which Multidrug-Resitant Bacteria are Emerging in Patients with Hematological Malignancies?: One-Year Report.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2015Article
- Bacterial Spectrum, Isolation Sites and Susceptibility Patterns of Pathogens in Adult Febrile Neutropenic Cancer Patients at a Specialist Hospital in Saudi Arabia.World journal of oncology · 2014Article
- Epidemiology of infections in cancer patients.Cancer treatment and research · 2014Review
- Applying Convergent Immunity to Innovative Vaccines Targeting Staphylococcus aureus.Frontiers in immunology · 2014Review
- The outcome of non-carbapenem-based empirical antibacterial therapy and VRE colonisation in patients with hematological malignancies.African health sciences · 2013Article
- Management of febrile neutropenia in the era of bacterial resistance.Therapeutic advances in infectious disease · 2013Review
- Using antimicrobial adjuvant therapy in cancer treatment: a review.Infectious agents and cancer · 2012Article
- Bloodstream infections and mortality-related factors in febrile neutropenic cancer patients.Medical science monitor : international medical journal of experimental and clinical research · 2011Article
- Increasing prevalence of nasal and rectal colonization with methicillin-resistant Staphylococcus aureus in children with cancer.Pediatric blood & cancer · 2010Article
- Infections in acute myeloid leukemia: an analysis of 382 febrile episodes.Medical oncology (Northwood, London, England) · 2010Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
goals of workFebrile neutropenia (FN) causes considerable morbidity in patients on cytotoxic chemotherapy. Recently, there has been a trend towards fewer Gram-negative and more Gram-positive infections with increasing antibiotic resistance. To assess these patterns, data from a supra-regional cancer centre in Ireland were reviewed. PATIENTS AND
methodsA 5-year review of all positive blood cultures in patients undergoing anti-cancer chemotherapy was carried out. MAIN
resultsEight hundred and ninety-four patients were reviewed. The mean incidence of FN was 64.2 cases per year. Eight hundred and forty-six blood culture specimens were taken and 173 (20.4%) were culture positive. The isolated organisms were Gram positive (71.1%), Gram negative (27.8%) and fungal (1.1%). Of the Gram-positive organisms, 75.6% were staphylococci. Of these, 67.8% were coagulase-negative staphylococci and 30.1% were Staphylococci aureus. Amongst the S. aureus, 89.3% were methicillin-resistant (MRSA). Vancomycin-resistant enterococci were not identified as a cause of positive blood cultures.
conclusionsAmongst patients with cancer who develop FN in our hospital, Gram-positive bacteria account for the largest proportion. The high proportion of MRSA as a cause of positive blood cultures is of concern.
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