ArticleThe Journal of cell biology1991
Subcellular localization and sequence of sea urchin kinesin heavy chain: evidence for its association with membranes in the mitotic apparatus and interphase cytoplasm.
Article in The Journal of cell biology, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed.
- Mitotic spindle membranes.Molecular biology of the cell · 2025Review
- Molecular mechanism for kinesin-1 direct membrane recognition.Science advances · 2021Article
- Fluorescence microscopy applied to intracellular transport by microtubule motors.Journal of biosciences · 2018Review
- Multiple kinesin motors coordinate cytoplasmic RNA transport on a subpopulation of microtubules in Xenopus oocytes.Developmental cell · 2008Article
- Analysis of cytoskeletal and motility proteins in the sea urchin genome assembly.Developmental biology · 2006Article
- Searching for a spindle matrix.The Journal of cell biology · 2001Article
- Mitosis, microtubules, and the matrix.The Journal of cell biology · 2001Review
- Clonal tests of conventional kinesin function during cell proliferation and differentiation.Molecular biology of the cell · 2000Article
- A specific light chain of kinesin associates with mitochondria in cultured cells.Molecular biology of the cell · 1998Article
- Kinesin- and myosin-driven steps of vesicle recruitment for Ca2+-regulated exocytosis.The Journal of cell biology · 1997Article
- Heterotrimeric kinesin-II is required for the assembly of motile 9+2 ciliary axonemes on sea urchin embryos.The Journal of cell biology · 1997Article
- Kinesin is essential for cell morphogenesis and polarized secretion in Neurospora crassa.The EMBO journal · 1997Article
- Fission yeast pkl1 is a kinesin-related protein involved in mitotic spindle function.Molecular biology of the cell · 1996Article
- Kinesin-II, a membrane traffic motor in axons, axonemes, and spindles.The Journal of cell biology · 1996Review
- Sequence and submolecular localization of the 115-kD accessory subunit of the heterotrimeric kinesin-II (KRP85/95) complex.The Journal of cell biology · 1996Article
- The Neurospora organelle motor: a distant relative of conventional kinesin with unconventional properties.Molecular biology of the cell · 1995Article
- Identification of the chromosome localization domain of the Drosophila nod kinesin-like protein.The Journal of cell biology · 1995Article
- Protein phosphatase 1 regulates the cytoplasmic dynein-driven formation of endoplasmic reticulum networks in vitro.The Journal of cell biology · 1995Article
- Kinesin is the motor for microtubule-mediated Golgi-to-ER membrane traffic.The Journal of cell biology · 1995Article
- Fast axonal transport of kinesin in the rat visual system: functionality of kinesin heavy chain isoforms.Molecular biology of the cell · 1995Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
Abstract
Kinesin was previously immunolocalized to mitotic apparatuses (MAs) of early sea urchin blastomeres (Scholey, J.M., M.E. Porter, P.M. Grissom, and J.R. McIntosh. 1985. Nature [Lond.]. 318:483-486). Here we report evidence that this MA-associated motor protein is a conventional membrane-bound kinesin, rather than a kinesin-like protein. Our evidence includes the observation that the deduced amino acid sequence of this sea urchin kinesin heavy chain is characteristic of a conventional kinesin. In addition, immunolocalizations using antibodies that distinguish kinesin from kinesin-like proteins confirm that conventional kinesin is concentrated in MAs. Finally, our immunocytochemical data further suggest that conventional kinesin is associated with membranes which accumulate in MAs and interphase asters of early sea urchin embryos, and with vesicles that are distributed in the perinuclear region of coelomocytes. Thus kinesin may function as a microtubule-based vesicle motor in some MAs, as well as in the interphase cytoplasm.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.