Evidence map›Paper›PMID 18274270›Full record

Trial reportSleep2008

Periodic leg movements predict total sleep time in persons with cognitive impairment and sleep disturbance.

Kathy C Richards, Paula K Roberson, Katherine Simpson, Corinne W Lambert, Donald L Bliwise, Catherine S Cole, Carol Enderlin, Valorie M Shue, Nadia Siddiqui, James Silas Williams

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Sleep, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00888706 (Effect of Activities and Exercise on Sleep in Dementia), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00888706 phase2completednot on this map

Effect of Activities and Exercise on Sleep in Dementia

TypeinterventionalSponsorNational Institute of Nursing Research (NINR)Ran2002 to 2008Enrolled355ConditionsDementia, Elderly, SleepArmsControl Condition, Individualized Social Activities (ISA), Physical Resistance Training and Walking (PRT/walking), Combined ISA/PRT/walking
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Sleep and Long-Term Care.Sleep medicine clinics · 2018
    Review
  2. Article
  3. Sleep disturbances in nursing homes.The journal of nutrition, health & aging · 2010
    Review
  4. Sleep disorders in aging and dementia.The journal of nutrition, health & aging · 2010
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kathy C RichardsPolisher Research Institute, Abramson Center for Jewish Life, Horsham, PA, USA. kcrichards@abramsoncenter.org
Paula K Roberson
Katherine Simpson
Corinne W Lambert
Donald L Bliwise
Catherine S Cole
Carol Enderlin
Valorie M Shue
Nadia Siddiqui
James Silas Williams

Funding

Verruca Vulgaris--Skin Test &Candida /Mumps AntigenM01RR014288 · NCRR · UNIV OF ARKANSAS FOR MED SCIS · PI FANN, ALICE · 1999 to 2006
$11.1M
UAMS Alzheimer's Disease Core CenterP30AG019606 · NIA · UNIVERSITY OF ARKANSAS MED SCIS LTL ROCK · PI BECK, CORNELIA MARIE · 2001 to 2005
$5.0M
Effect of Activities and Exercise on Sleep in DementiaR01NR007771 · NINR · UNIV OF ARKANSAS FOR MED SCIS · PI RICHARDS, KATHY CULPEPPER · 2002 to 2006
$2.2M
NCRR NIH HHS M01 RR014288NCRR NIH HHS M01RR14288NIA NIH HHS P30 AG019606NIA NIH HHS P30AG19606NINR NIH HHS R01 NR007771NINR NIH HHS R01-NR-007771
6 · The paper itself

Abstract

STUDY

objectiveTo determine if periodic leg movements predict total sleep time at night in elders with cognitive impairment and sleep disturbance.

designDescriptive cross-sectional secondary analysis using data from an observational study and baseline data from a randomized, controlled clinical trial. SETTINGS: Private homes, nursing homes, and assisted living facilities.

participantsOne hundred and two persons with a mean age of 81.8 years, cognitive impairment, and sleep disturbance.

interventionN/A. MEASUREMENTS AND

resultsWe measured sleep variables using 1 night of attended polysomnography in each participant's usual sleep setting. We assessed 10 characteristics associated with sleep disturbance (periodic leg movement index, time in bed, apnea-hypopnea index, oxygen saturation nadir, age, sex, living arrangement, cognitive status, painful conditions, and depression) with multiple linear regression analyses to determine the predictors of total sleep time. Of the 102 participants, 56.9% were men, and 64.7% lived in nursing homes or assisted living facilities. Their mean Mini-Mental State Examination score was 17.3. In addition, 21.6% had 1 or more painful conditions, and 45.1% were diagnosed with depression. Participants' mean periodic leg movement index was 17.3 with 34 (33.3%) having a periodic leg movement index greater than 15. Time in bed at night exceeded 8 hours, yet participants averaged only 5.5 hours of sleep. They had a mean apnea-hypopnea index of 18.3, with a mean oxygen saturation nadir of 86.4%. Periodic leg movement index, time in bed, and age explained 43.6% of the variance in total sleep time.

conclusionsFrequent periodic leg movements, less time in bed, and older age are associated with less sleep at night in this population.

Indexed as

AgedAged, 80 and overCognition DisordersCross-Sectional StudiesFemaleHumansMaleMiddle AgedNeuropsychological TestsNocturnal Myoclonus SyndromePolysomnographyPrevalenceProspective StudiesSeverity of Illness IndexSleep Wake DisordersTime Factors

Identifiers

PMID18274270
PMCPMC2225566

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.