Evidence map›Paper›PMID 18272714›Full record

ArticleJournal of clinical microbiology2008

Genetic diversity of Mycobacterium avium isolates recovered from clinical samples and from the environment: molecular characterization for diagnostic purposes.

Julio Alvarez, Ignacio Gómez García, Alicia Aranaz, Javier Bezos, Beatriz Romero, Lucía de Juan, Ana Mateos, Enrique Gómez-Mampaso, Lucas Domínguez

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Case - Penile mycobacterium avium complex infection.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2026
    Article
  2. Isolation of Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2024
    Article
  3. Article
  4. Detection of theIranian journal of veterinary research · 2023
    Article
  5. Spatial and Temporal Distribution ofAnimals : an open access journal from MDPI · 2021
    Article
  6. Genetic Involvement ofInternational journal of molecular sciences · 2021
    Review
  7. Differential Genotyping ofMicroorganisms · 2020
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Julio AlvarezDepartamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, 28040 Madrid, Spain. alaranaz@vet.ucm.es
Ignacio Gómez García
Alicia Aranaz
Javier Bezos
Beatriz Romero
Lucía de Juan
Ana Mateos
Enrique Gómez-Mampaso
Lucas Domínguez

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Isolation of Mycobacterium avium complex (MAC) organisms from clinical samples may occur in patients without clinical disease, making the interpretation of results difficult. The clinical relevance of MAC isolates from different types of clinical samples (n = 47) from 39 patients in different sections of a hospital was assessed by comparison with environmental isolates (n = 17) from the hospital. Various methods for identification and typing (commercial probes, phenotypic characteristics, PCR for detection of IS1245 and IS901, sequencing of the hsp65 gene, and pulsed-field gel electrophoresis) were evaluated. The same strain was found in all the environmental isolates, 21 out of 23 (91.3%) of the isolates cultured from urine samples, and 5 out of 19 (26.3%) isolates from respiratory specimens. This strain did not cause disease in the patients. Testing best characterized the strain as M. avium subsp. hominissuis, with the unusual feature that 81.4% of these isolates lacked the IS1245 element. Contamination of certain clinical samples with an environmental strain was the most likely event; therefore, characterization of the environmental mycobacteria present in health care facilities should be performed to discard false-positive isolations in nonsterile samples, mainly urine samples. Molecular techniques applied in this study demonstrated their usefulness for this purpose.

Indexed as

Genetic VariationMycobacterium avium ComplexMycobacterium avium-intracellulare InfectionWater SupplyBacterial ProteinsBacterial Typing TechniquesChaperonin 60ChaperoninsDNA Transposable ElementsElectrophoresis, Gel, Pulsed-FieldEquipment and Supplies, HospitalFresh WaterHospitalsHumansPolymerase Chain ReactionSputumBacterial ProteinsChaperonin 60ChaperoninsDNA Transposable Elementsheat-shock protein 65, Mycobacterium

Identifiers

PMID18272714
PMCPMC2292972

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.